VeriMomIs neopentyl glycol diethylhexanoate safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
neopentyl glycol diethylhexanoate
HIGH RISK33
/100
0
Pregnancy-Safe Alternatives to neopentyl glycol diethylhexanoate | VeriMom
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Frequently asked questions
- Is neopentyl glycol diethylhexanoate safe during pregnancy?
- CIR's expert review notes neopentyl glycol diethylhexanoate is likely absorbed and metabolized and that its metabolite 2‑ethylhexanoic acid is a liver and reproductive toxicant; animal studies of 2‑EHA show developmental effects, supporting a 'suspected' reproductive hazard. (CIR assessment; PubMed animal studies). https://cir-safety.org/sites/default/files/glycol%20esters.pdf; https://pubmed.ncbi.nlm.nih.gov/8405783/.
- Is neopentyl glycol diethylhexanoate safe while breastfeeding?
- Hazard and mechanism mirror pregnancy because the same metabolite (2‑EHA) and animal developmental data apply; there are no human lactation transfer data but the parent is absorbable and metabolized so lactational exposure cannot be excluded. (CIR; animal studies on 2‑EHA). https://cir-safety.org/sites/default/files/glycol%20esters.pdf; https://pubmed.ncbi.nlm.nih.gov/8449392/.
- Is neopentyl glycol diethylhexanoate safe for baby skin?
- Same suspected hazard (via metabolite 2‑EHA) and demonstrated developmental toxicity in animals informs hazard and mechanism. Exposure score increased by +1 for infants because CIR indicates the ingredient is absorbable and it is used in leave‑on products (reported up to 57%), and infant skin has higher uptake per weight. (CIR concentration/use and metabolism notes). https://cir-safety.org/sites/default/files/glycol%20esters.pdf.
- How does VeriMom score neopentyl glycol diethylhexanoate?
- VeriMom scores neopentyl glycol diethylhexanoate at 33/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to neopentyl glycol diethylhexanoate?
- See our curated list of pregnancy-safe alternatives to neopentyl glycol diethylhexanoate based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.