Стоит ли избегать neopentyl glycol diethylhexanoate при беременности? | VeriMom

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Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли neopentyl glycol diethylhexanoate при беременности?

CIR's expert review notes neopentyl glycol diethylhexanoate is likely absorbed and metabolized and that its metabolite 2‑ethylhexanoic acid is a liver and reproductive toxicant; animal studies of 2‑EHA show developmental effects, supporting a 'suspected' reproductive hazard. (CIR assessment; PubMed animal studies). https://cir-safety.org/sites/default/files/glycol%20esters.pdf; https://pubmed.ncbi.nlm.nih.gov/8405783/.

Безопасен ли neopentyl glycol diethylhexanoate при грудном вскармливании?

Hazard and mechanism mirror pregnancy because the same metabolite (2‑EHA) and animal developmental data apply; there are no human lactation transfer data but the parent is absorbable and metabolized so lactational exposure cannot be excluded. (CIR; animal studies on 2‑EHA). https://cir-safety.org/sites/default/files/glycol%20esters.pdf; https://pubmed.ncbi.nlm.nih.gov/8449392/.

Безопасен ли neopentyl glycol diethylhexanoate для кожи малыша?

Same suspected hazard (via metabolite 2‑EHA) and demonstrated developmental toxicity in animals informs hazard and mechanism. Exposure score increased by +1 for infants because CIR indicates the ingredient is absorbable and it is used in leave‑on products (reported up to 57%), and infant skin has higher uptake per weight. (CIR concentration/use and metabolism notes). https://cir-safety.org/sites/default/files/glycol%20esters.pdf.

Как VeriMom оценивает neopentyl glycol diethylhexanoate?

VeriMom оценивает neopentyl glycol diethylhexanoate в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы neopentyl glycol diethylhexanoate при беременности?

См. наш список безопасных альтернатив neopentyl glycol diethylhexanoate с аналогичной функцией и классификацией без известных рисков.