VeriMomБезопасен ли n,n'-methylenebisacrylamide при беременности?
There are peer‑reviewed developmental toxicity studies in mice reporting decreased fetal body weight and increased fetal variations with N,N'-methylenebisacrylamide (110-26-9), indicating suspected developmental hazard (NOAEL for developmental toxicity reported at 3 mg/kg/day; adverse effects at higher doses). No harmonised CLP (Annex VI) reproductive classification was identified. For typical topical cosmetic use, dermal exposure/absorption from finished products is expected to be negligible. (Toxicological Sciences 1998; ECHA substance information; product SDSs/MSDSs reporting reproductive hazard category in supplier documents).
Безопасные альтернативы n,n'-methylenebisacrylamide при беременности | VeriMom
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Frequently asked questions
- Безопасен ли n,n'-methylenebisacrylamide при беременности?
- There are peer‑reviewed developmental toxicity studies in mice reporting decreased fetal body weight and increased fetal variations with N,N'-methylenebisacrylamide (110-26-9), indicating suspected developmental hazard (NOAEL for developmental toxicity reported at 3 mg/kg/day; adverse effects at higher doses). No harmonised CLP (Annex VI) reproductive classification was identified. For typical topical cosmetic use, dermal exposure/absorption from finished products is expected to be negligible. (Toxicological Sciences 1998; ECHA substance information; product SDSs/MSDSs reporting reproductive hazard category in supplier documents).
- Безопасен ли n,n'-methylenebisacrylamide при грудном вскармливании?
- Same basis as pregnancy: animal developmental/reproductive studies show suspected developmental toxicity. There are no data showing transfer into human milk; for normal topical cosmetic use, exposure to a nursing infant via maternal milk is expected to be negligible. No authoritative cosmetic‑safety body (CIR/SCCS) reproductive clearance for this specific compound was located.
- Безопасен ли n,n'-methylenebisacrylamide для кожи малыша?
- The hazard evidence (mouse developmental toxicity) supports a suspected reproductive/developmental hazard. Dermal exposure of infants (0–3 yr) is of greater concern than for adults because immature skin has higher surface‑area‑to‑weight and higher relative uptake; while adult topical cosmetic exposure is expected to be negligible, per the scoring rules infant exposure is increased by +1 when measurable absorption cannot be excluded. There are no infant‑specific toxicity data identified.
- Как VeriMom оценивает n,n'-methylenebisacrylamide?
- VeriMom оценивает n,n'-methylenebisacrylamide в 39/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы n,n'-methylenebisacrylamide при беременности?
- См. наш список безопасных альтернатив n,n'-methylenebisacrylamide с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.