VeriMomБезопасен ли magnolia kobus bark extract при беременности?
No EU ban/restriction or harmonised CMR classification found for Magnolia kobus bark extract/CAS 223749-80-2 (CosIng entry exists), but animal studies on major Magnolia bark constituents (honokiol, magnolol) report embryo–fetal effects or placental/uterine effects in rodents, so reproductive hazard is suspected. Example studies: an embryo–fetal toxicity study of honokiol in pregnant rats and animal data showing magnolol alters placental morphology and can inhibit uterine contraction. CosIng/industry listings and EWG do not override these animal findings. Sources: PubMed studies and WHO monograph noted below.
Pregnancy-safe products containing magnolia kobus bark extract
Безопасные альтернативы magnolia kobus bark extract при беременности | VeriMom
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Frequently asked questions
- Безопасен ли magnolia kobus bark extract при беременности?
- No EU ban/restriction or harmonised CMR classification found for Magnolia kobus bark extract/CAS 223749-80-2 (CosIng entry exists), but animal studies on major Magnolia bark constituents (honokiol, magnolol) report embryo–fetal effects or placental/uterine effects in rodents, so reproductive hazard is suspected. Example studies: an embryo–fetal toxicity study of honokiol in pregnant rats and animal data showing magnolol alters placental morphology and can inhibit uterine contraction. CosIng/industry listings and EWG do not override these animal findings. Sources: PubMed studies and WHO monograph noted below.
- Безопасен ли magnolia kobus bark extract при грудном вскармливании?
- No harmonised classification or EU Annex II/III listing found; however the same animal data and mechanistic evidence (placental/uterine activity and systemic activity of isolated constituents) justify a suspected hazard and demonstrated mechanism. Transfer into breastmilk is not directly studied for the extract, but systemic bioactivity of honokiol/magnolol supports cautious classification as suspected (h=2). Exposure from topical cosmetic use is likely low but measurable.
- Безопасен ли magnolia kobus bark extract для кожи малыша?
- Baby skin exposure: do not increase h or m without infant-specific evidence, but exposure score is increased because infant skin has higher absorption. The ingredient contains small lipophilic active constituents (honokiol/magnolol) with demonstrated systemic activity in animals; therefore exposure for 0–3 yr olds is scored higher (adult e=1 → baby e=2). No infant-specific safety studies located.
- Как VeriMom оценивает magnolia kobus bark extract?
- VeriMom оценивает magnolia kobus bark extract в 40/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы magnolia kobus bark extract при беременности?
- См. наш список безопасных альтернатив magnolia kobus bark extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.