Безопасен ли resveratryl tris-ethylhexanoate при беременности?

Безопасные альтернативы resveratryl tris-ethylhexanoate при беременности | VeriMom

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Безопасен ли resveratryl tris-ethylhexanoate при беременности?

No EU Annex II/III listing or harmonised CLP classification was found for this substance; no SCCS/CIR safety assessment specific to resveratryl tris‑ethylhexanoate was found. However, it is derived from resveratrol, a phytoestrogen with in vitro estrogenic activity and some reported endocrine‑related effects in the literature (resveratrol class = structural/biochemical alert), so a class/structural‑alert flag is applied (h=1). Mechanistically this is theoretical only (m=1) because the concern is based on parent resveratrol’s in vitro endocrine activity and possible metabolic release — no direct in vivo developmental/reproductive studies on this specific ester were located. Absorption from topical use is likely low but measurable (e=1) given the ester is lipophilic and intended for topical formulations; no dermal absorption data for this exact ester were found.

Безопасен ли resveratryl tris-ethylhexanoate при грудном вскармливании?

Same justification as pregnancy: no direct reproductive/breastmilk transfer data for this specific ingredient. Because it is a resveratrol derivative, a conservative structural/class alert is applied (h=1) and mechanism remains theoretical (m=1). Exposure from topical application to the breast is expected to be low but measurable (e=1); no data were found on transfer into breastmilk for this ester.

Безопасен ли resveratryl tris-ethylhexanoate для кожи малыша?

No infant‑specific safety studies for resveratryl tris‑ethylhexanoate were identified. Hazard and mechanism scores remain the same as adult (h=1, m=1) because there is no infant‑specific evidence of increased hazard or a different mechanism. Exposure score is increased by +1 (e=2) to account for higher per‑weight exposure and immature barrier in 0–3‑year‑old skin when the ingredient has measurable dermal absorption in adults.

Как VeriMom оценивает resveratryl tris-ethylhexanoate?

VeriMom оценивает resveratryl tris-ethylhexanoate в 67/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы resveratryl tris-ethylhexanoate при беременности?

См. наш список безопасных альтернатив resveratryl tris-ethylhexanoate с аналогичной функцией и классификацией без известных рисков.