VeriMomБезопасен ли darutoside при беременности?
Animal evidence: an experimental rat study reported that darutoside caused termination of early pregnancy at 20–40 mg/kg, indicating a suspected reproductive/abortifacient effect in animals (PubMed). No harmonised CLP classification, SCCS opinion, or CIR safety assessment for darutoside was found to contradict this, so the animal finding drives a 'suspected' score. Topical cosmetic use likely gives low but measurable systemic exposure (glycoside, used at low % in formulations), so exposure rated low (e=1).
Pregnancy-safe products containing darutoside
Безопасные альтернативы darutoside при беременности | VeriMom
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Frequently asked questions
- Безопасен ли darutoside при беременности?
- Animal evidence: an experimental rat study reported that darutoside caused termination of early pregnancy at 20–40 mg/kg, indicating a suspected reproductive/abortifacient effect in animals (PubMed). No harmonised CLP classification, SCCS opinion, or CIR safety assessment for darutoside was found to contradict this, so the animal finding drives a 'suspected' score. Topical cosmetic use likely gives low but measurable systemic exposure (glycoside, used at low % in formulations), so exposure rated low (e=1).
- Безопасен ли darutoside при грудном вскармливании?
- No data on transfer into human milk or lactation-specific studies were found; the same animal reproductive signal supports a suspected hazard (h=2) but there is no demonstrated mechanism of milk transfer. Dermal/topical use would likely result in low but potentially measurable systemic exposure in adults (e=1).
- Безопасен ли darutoside для кожи малыша?
- No infant-specific toxicology available. Per your guidance, because darutoside shows an animal reproductive effect and topical use has measurable absorption in adults, baby skin exposure is increased by +1 (adult e=1 → baby e=2) to account for immature barrier and higher surface-area-to-weight; hazard and mechanism scores are not increased without infant-specific evidence. No regulatory body (harmonised CLP, SCCS, CIR) provides a contrary safety opinion. (See sources below.)
- Как VeriMom оценивает darutoside?
- VeriMom оценивает darutoside в 47/100 (средний риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы darutoside при беременности?
- См. наш список безопасных альтернатив darutoside с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.