Безопасен ли basic yellow 57 при беременности?

Безопасные альтернативы basic yellow 57 при беременности | VeriMom

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См. также

• Безопасен ли basic yellow 57 для малышей?
• Стоит ли избегать basic yellow 57 при беременности?
• Какие безопасные при беременности альтернативы basic yellow 57?

Frequently asked questions

Безопасен ли basic yellow 57 при беременности?

Animal developmental studies report fetal malformations at very high oral doses (developmental NOAEL corrected ≈237 mg/kg bw/day; adverse effects at 1000 mg/kg in rats), supporting suspected developmental hazard based on animal data. The ingredient does not have a harmonised H360 classification, but animal reproductive/developmental findings justify h=2 (suspected). Dermal absorption from representative cosmetic formulations is low but measurable in in vitro pig skin studies (2–4% bioavailable after 48 h) and reported cosmetic uses are primarily hair dyes at low concentrations, so exposure from normal topical cosmetic use is low but non‑negligible. (CIR safety assessment; SCCS summary; ECHA substance record).

Безопасен ли basic yellow 57 при грудном вскармливании?

No human lactation studies were located. Animal developmental/reprotoxic findings indicate a suspected hazard (h=2). There is no evidence of a specific reproductive mechanism or documented transfer into milk; dermal systemic absorption from cosmetic use is low but measurable so maternal systemic exposure (and therefore potential, but likely low, transfer into breastmilk) is possible. (CIR; ECHA).

Безопасен ли basic yellow 57 для кожи малыша?

Hazard score follows the animal developmental data (h=2). Mechanistic data for developmental/ endocrine modes of action were not identified (m=0). Measurable dermal bioavailability in in vitro skin studies (2–4% over 48 h) means exposure on infant skin is higher relative to adults due to immature barrier and higher surface‑area‑to‑weight; per scoring rules increase exposure by +1 giving e=2 for 0–3 y infants. No infant‑specific absorption studies were found. (CIR dermal absorption data; SCCS/CIR use‑levels).

Как VeriMom оценивает basic yellow 57?

VeriMom оценивает basic yellow 57 в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы basic yellow 57 при беременности?

См. наш список безопасных альтернатив basic yellow 57 с аналогичной функцией и классификацией без известных рисков.