VeriMomСтоит ли избегать basic yellow 57 при беременности? | VeriMom
Animal developmental studies report fetal malformations at very high oral doses (developmental NOAEL corrected ≈237 mg/kg bw/day; adverse effects at 1000 mg/kg in rats), supporting suspected developmental hazard based on animal data. The ingredient does not have a harmonised H360 classification, but animal reproductive/developmental findings justify h=2 (suspected). Dermal absorption from representative cosmetic formulations is low but measurable in in vitro pig skin studies (2–4% bioavailable after 48 h) and reported cosmetic uses are primarily hair dyes at low concentrations, so exposure from normal topical cosmetic use is low but non‑negligible. (CIR safety assessment; SCCS summary; ECHA substance record).
ECHA regulatory hazard statements
- •H361D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли basic yellow 57 при беременности?
- Animal developmental studies report fetal malformations at very high oral doses (developmental NOAEL corrected ≈237 mg/kg bw/day; adverse effects at 1000 mg/kg in rats), supporting suspected developmental hazard based on animal data. The ingredient does not have a harmonised H360 classification, but animal reproductive/developmental findings justify h=2 (suspected). Dermal absorption from representative cosmetic formulations is low but measurable in in vitro pig skin studies (2–4% bioavailable after 48 h) and reported cosmetic uses are primarily hair dyes at low concentrations, so exposure from normal topical cosmetic use is low but non‑negligible. (CIR safety assessment; SCCS summary; ECHA substance record).
- Безопасен ли basic yellow 57 при грудном вскармливании?
- No human lactation studies were located. Animal developmental/reprotoxic findings indicate a suspected hazard (h=2). There is no evidence of a specific reproductive mechanism or documented transfer into milk; dermal systemic absorption from cosmetic use is low but measurable so maternal systemic exposure (and therefore potential, but likely low, transfer into breastmilk) is possible. (CIR; ECHA).
- Безопасен ли basic yellow 57 для кожи малыша?
- Hazard score follows the animal developmental data (h=2). Mechanistic data for developmental/ endocrine modes of action were not identified (m=0). Measurable dermal bioavailability in in vitro skin studies (2–4% over 48 h) means exposure on infant skin is higher relative to adults due to immature barrier and higher surface‑area‑to‑weight; per scoring rules increase exposure by +1 giving e=2 for 0–3 y infants. No infant‑specific absorption studies were found. (CIR dermal absorption data; SCCS/CIR use‑levels).
- Как VeriMom оценивает basic yellow 57?
- VeriMom оценивает basic yellow 57 в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы basic yellow 57 при беременности?
- См. наш список безопасных альтернатив basic yellow 57 с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.