VeriMomIst apigenin in der Schwangerschaft sicher?
No EU Annex II/III listing or harmonised CLP reproductive/CMR classification was found for apigenin (CAS 520-36-5), and no authoritative CIR/SCCS safety opinion identifying a reproductive hazard was found; peer‑reviewed literature reports in‑vitro estrogenic/sex‑hormone–modulating activity for apigenin (mechanistic evidence) but not clear human teratogenic or harmonised animal reproductive hazard leading to regulatory classification, so hazard = 0; mechanism = 2 because in‑vitro estrogenic and endocrine‑modulating activity has been demonstrated. Topical dermal absorption from cosmetics is reported as low but measurable depending on formulation (ex vivo permeation varies with vehicle), therefore exposure = 1. � Sources: PubMed/PMC reviews on apigenin bioactivity and skin use; ex vivo skin permeation review; COSING/ingredient databases.
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Frequently asked questions
- Ist apigenin in der Schwangerschaft sicher?
- No EU Annex II/III listing or harmonised CLP reproductive/CMR classification was found for apigenin (CAS 520-36-5), and no authoritative CIR/SCCS safety opinion identifying a reproductive hazard was found; peer‑reviewed literature reports in‑vitro estrogenic/sex‑hormone–modulating activity for apigenin (mechanistic evidence) but not clear human teratogenic or harmonised animal reproductive hazard leading to regulatory classification, so hazard = 0; mechanism = 2 because in‑vitro estrogenic and endocrine‑modulating activity has been demonstrated. Topical dermal absorption from cosmetics is reported as low but measurable depending on formulation (ex vivo permeation varies with vehicle), therefore exposure = 1. � Sources: PubMed/PMC reviews on apigenin bioactivity and skin use; ex vivo skin permeation review; COSING/ingredient databases.
- Ist apigenin während des Stillens sicher?
- Same rationale as pregnancy: no regulatory reproductive/CMR classification or CIR/SCCS restriction found. Mechanistic data show apigenin can modulate hormone pathways (in vitro) which is relevant to lactation physiology but no convincing data show human reproductive or lactation toxicity. Dermal exposure from cosmetics is low but measurable, so adult breastfeeding exposure = 1. Sources: peer‑reviewed reviews on apigenin pharmacology and topical use; COSING/EWG entries.
- Ist apigenin sicher für Babyhaut?
- No infant‑specific developmental toxicity or dermal teratogenicity data were found and no regulatory ban/restriction for apigenin. Mechanistic evidence (in‑vitro estrogenic/endocrine‑modulating activity) remains (m=2). Exposure score increased by +1 for infants (e=2) because topical absorption through infant skin is higher (immature barrier, higher surface‑area‑to‑weight) and formulation/permeation studies show apigenin can permeate skin depending on vehicle; therefore infant dermal exposure is likely higher than adult. Sources: reviews showing skin permeation and cosmetic use, PubMed mechanistic literature, COSING database.
- Wie bewertet VeriMom apigenin?
- VeriMom bewertet apigenin mit 80/100 (geringes Risiko) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
- Was sind schwangerschaftssichere Alternativen zu apigenin?
- Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu apigenin basierend auf ähnlicher Funktion.
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Medizinischer Haftungsausschluss
Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.