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HIGH RISK

Should I Avoid diethylenetriamine During Pregnancy? | VeriMom

Reviewed by · Last reviewed

ECHA regulatory hazard statements

  • H312
  • H302
  • H314
  • H317

Products containing diethylenetriamine — check your shelf

These products list diethylenetriamine on their INCI. If one is in your routine, consider swapping it during pregnancy.

What to use instead

Pregnancy-safe ingredients that serve a similar function:

Pregnancy-safe products to use instead

Products built around the safer ingredients above, scored "no known risks" or "low risk".

Sources & references

Authoritative references used to score this ingredient.

Pregnancy-Safe Alternatives to diethylenetriamine | VeriMom

IngredientsPregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated

See also

FAQ

Is diethylenetriamine safe during pregnancy?
ECHA/CLP lists diethylenetriamine (CAS 111-40-0) with a harmonised reproductive classification (Repr. 1B / H360 — “may damage fertility or the unborn child”), which per your scoring rules requires h=3. Registrations/REACH dossiers report reproduction screening studies (OECD 421) with parental/offspring effects at tested doses, supporting concern; no clear, well-described molecular mechanism was located in the reviewed sources, so m=0. As a cosmetic topical exposure scenario, systemic exposure is expected to be low but measurable (e=1).
Is diethylenetriamine safe while breastfeeding?
Because the substance has a harmonised H360 (Repr. 1B) classification at the EU level, the reproductive hazard score remains h=3 for breastfeeding (harm to reproduction includes potential effects relevant to offspring). No direct mechanism for transfer into milk was identified (m=0). For typical topical cosmetic use systemic exposure is low but measurable (e=1); if systemic maternal exposure occurred, transfer to breastmilk could be possible but specific milk transfer data were not found.
Is diethylenetriamine safe for baby skin?
Hazard remains h=3 because of the harmonised H360 classification. No infant-specific mechanism data were found (m=0). Per your rule to increase exposure by +1 for baby skin when the adult exposure is measurable, adult e=1 becomes e=2 for infants (higher surface-area-to-weight and immature barrier). No infant dermal absorption studies were located in the reviewed sources.
How does VeriMom score diethylenetriamine?
VeriMom scores diethylenetriamine at 33/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to diethylenetriamine?
See our curated list of pregnancy-safe alternatives to diethylenetriamine based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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