VeriMomБезопасен ли diethylenetriamine при беременности?
ECHA/CLP lists diethylenetriamine (CAS 111-40-0) with a harmonised reproductive classification (Repr. 1B / H360 — “may damage fertility or the unborn child”), which per your scoring rules requires h=3. Registrations/REACH dossiers report reproduction screening studies (OECD 421) with parental/offspring effects at tested doses, supporting concern; no clear, well-described molecular mechanism was located in the reviewed sources, so m=0. As a cosmetic topical exposure scenario, systemic exposure is expected to be low but measurable (e=1).
Безопасные альтернативы diethylenetriamine при беременности | VeriMom
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Frequently asked questions
- Безопасен ли diethylenetriamine при беременности?
- ECHA/CLP lists diethylenetriamine (CAS 111-40-0) with a harmonised reproductive classification (Repr. 1B / H360 — “may damage fertility or the unborn child”), which per your scoring rules requires h=3. Registrations/REACH dossiers report reproduction screening studies (OECD 421) with parental/offspring effects at tested doses, supporting concern; no clear, well-described molecular mechanism was located in the reviewed sources, so m=0. As a cosmetic topical exposure scenario, systemic exposure is expected to be low but measurable (e=1).
- Безопасен ли diethylenetriamine при грудном вскармливании?
- Because the substance has a harmonised H360 (Repr. 1B) classification at the EU level, the reproductive hazard score remains h=3 for breastfeeding (harm to reproduction includes potential effects relevant to offspring). No direct mechanism for transfer into milk was identified (m=0). For typical topical cosmetic use systemic exposure is low but measurable (e=1); if systemic maternal exposure occurred, transfer to breastmilk could be possible but specific milk transfer data were not found.
- Безопасен ли diethylenetriamine для кожи малыша?
- Hazard remains h=3 because of the harmonised H360 classification. No infant-specific mechanism data were found (m=0). Per your rule to increase exposure by +1 for baby skin when the adult exposure is measurable, adult e=1 becomes e=2 for infants (higher surface-area-to-weight and immature barrier). No infant dermal absorption studies were located in the reviewed sources.
- Как VeriMom оценивает diethylenetriamine?
- VeriMom оценивает diethylenetriamine в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы diethylenetriamine при беременности?
- См. наш список безопасных альтернатив diethylenetriamine с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.