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Is trimethylhexanol safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
trimethylhexanol
HIGH RISK
33
/100
0

Pregnancy-Safe Alternatives to trimethylhexanol | VeriMom

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Frequently asked questions

Is trimethylhexanol safe during pregnancy?
No harmonised ECHA Annex VI classification (H360/H361) was found; available H361 labels appear on supplier SDS/product listings and not as an EU-harmonised C&L entry. REACH/ECHA contains a registration dossier for 3,5,5-trimethylhexan-1-ol (CAS 3452-97-9) but I found no SCCS or CIR reproductive safety assessment nor peer‑reviewed studies demonstrating reproductive toxicity. Given limited evidence of systemic reproductive hazard, hazard (h)=0. Dermal exposure from cosmetic use is plausible but low-to-measurable for a C9 primary alcohol (e=1). Sources: ECHA substance/registration pages, PubChem, supplier SDSs/C&L listings.
Is trimethylhexanol safe while breastfeeding?
No data showing effects in lactation or transfer via milk; no mechanistic data for reproductive or endocrine activity found. As for pregnancy, hazard and mechanism scores default to 0. Low but measurable dermal absorption expected in typical cosmetic use (e=1).
Is trimethylhexanol safe for baby skin?
No infant-specific toxicology identified. Per your rules, when an ingredient has measurable dermal absorption in adults increase exposure score by +1 for infants — adult e=1 → baby e=2. No evidence to raise hazard or mechanism scores for infants.
How does VeriMom score trimethylhexanol?
VeriMom scores trimethylhexanol at 33/100 (high risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to trimethylhexanol?
See our curated list of pregnancy-safe alternatives to trimethylhexanol based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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