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Is sh-polypeptide-1 safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
sh-polypeptide-1
NO KNOWN RISKS
100
/100
0

Pregnancy-safe products containing sh-polypeptide-1

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Authoritative references used to score this ingredient.

Frequently asked questions

Is sh-polypeptide-1 safe during pregnancy?
No harmonised CLP reproductive classification (ECHA Annex VI) or SCCS/CIR safety restriction found for SH‑Polypeptide‑1; as a large hydrophilic peptide (EGF analogue) topical systemic absorption is expected to be negligible and there are no published reproductive/teratogenic signals in the regulatory literature (CIR, ECHA, CosIng) or dominant peer‑reviewed sources (PubMed). Thus default hazard/mechanism scores are 0 and exposure is scored 0.
Is sh-polypeptide-1 safe while breastfeeding?
Same rationale as pregnancy: no regulatory reproductive/teratogenic flags, no mechanistic data indicating placental/mammary transfer or endocrine disruption. Topical absorption of a peptide like SH‑Polypeptide‑1 is negligible, so breastfeeding exposure is expected to be negligible.
Is sh-polypeptide-1 safe for baby skin?
Hazard and mechanism: no infant‑specific reproductive/toxicity evidence or regulatory flags. Exposure: adult topical dermal absorption is expected negligible (e=0), but infant skin has higher absorption potential; per the requested calibration, increase exposure by +1 for baby skin (e=1). There is no evidence to increase hazard or mechanism scores for infants.
How does VeriMom score sh-polypeptide-1?
VeriMom scores sh-polypeptide-1 at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to sh-polypeptide-1?
See our curated list of pregnancy-safe alternatives to sh-polypeptide-1 based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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