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Is salicyloyl oligopeptide-143 safe during pregnancy?

No harmonised CLP classification, no CIR or SCCS safety assessment specifically for salicyloyl oligopeptide-143, and no peer‑reviewed reproductive/toxicity studies identified (sources searched: ECHA Annex VI, CIR, SCCS, PubMed, ECHA dossiers, CosIng, PubChem, EWG). The only plausible theoretical concern is that the salicyloyl group could release salicylic acid, but there is no direct evidence that this ingredient causes reproductive toxicity. Therefore hazard = 0 (no evidence), mechanism = 1 (theoretical only: potential release of salicylate), exposure = 1 (topical cosmetic use — low but potentially measurable absorption).

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
salicyloyl oligopeptide-143
LOW RISK
87
/100
0

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Frequently asked questions

Is salicyloyl oligopeptide-143 safe during pregnancy?
No harmonised CLP classification, no CIR or SCCS safety assessment specifically for salicyloyl oligopeptide-143, and no peer‑reviewed reproductive/toxicity studies identified (sources searched: ECHA Annex VI, CIR, SCCS, PubMed, ECHA dossiers, CosIng, PubChem, EWG). The only plausible theoretical concern is that the salicyloyl group could release salicylic acid, but there is no direct evidence that this ingredient causes reproductive toxicity. Therefore hazard = 0 (no evidence), mechanism = 1 (theoretical only: potential release of salicylate), exposure = 1 (topical cosmetic use — low but potentially measurable absorption).
Is salicyloyl oligopeptide-143 safe while breastfeeding?
Same rationale as pregnancy. No specific data showing transfer into milk or effects on lactation; theoretical concern only via possible salicylate release. For normal cosmetic topical use exposure is expected to be low.
Is salicyloyl oligopeptide-143 safe for baby skin?
No infant-specific toxicology or clinical data located. Hazard remains 0 (no evidence). Mechanistic concern is theoretical only (possible salicyloyl → salicylic acid). Exposure score increased by +1 for infants due to immature barrier and higher surface‑area‑to‑weight, so e = 2 (moderate relative exposure).
How does VeriMom score salicyloyl oligopeptide-143?
VeriMom scores salicyloyl oligopeptide-143 at 87/100 (low risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to salicyloyl oligopeptide-143?
See our curated list of pregnancy-safe alternatives to salicyloyl oligopeptide-143 based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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