punica granatum pericarp extract est-il sûr pendant la grossesse ?
No harmonised CLP reproductive classifications (ECHA Annex VI) or SCCS/CIR safety assessment listing this ingredient as a reproductive/teratogenic hazard; therefore no confirmed reproductive hazard. However, peer-reviewed in vitro studies report estrogen-receptor modulatory activity for pomegranate extracts/constituents (PubMed), which is a demonstrated molecular activity relevant to reproductive endocrine pathways, so mechanism is scored above theoretical. Topical cosmetic exposure is expected to give negligible systemic absorption in adults (CosIng/PubChem context; no evidence of systemic reproductive toxicity).
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Frequently asked questions
- punica granatum pericarp extract est-il sûr pendant la grossesse ?
- No harmonised CLP reproductive classifications (ECHA Annex VI) or SCCS/CIR safety assessment listing this ingredient as a reproductive/teratogenic hazard; therefore no confirmed reproductive hazard. However, peer-reviewed in vitro studies report estrogen-receptor modulatory activity for pomegranate extracts/constituents (PubMed), which is a demonstrated molecular activity relevant to reproductive endocrine pathways, so mechanism is scored above theoretical. Topical cosmetic exposure is expected to give negligible systemic absorption in adults (CosIng/PubChem context; no evidence of systemic reproductive toxicity).
- punica granatum pericarp extract est-il sûr pendant l'allaitement ?
- No evidence of harm to lactation or breastfed infants, and no harmonised reproductive classification. Same in vitro ER-modulatory activity applies (mechanism=demonstrated). With typical topical cosmetic use, systemic absorption in adults is expected to be negligible, so transfer into breastmilk is unlikely based on available regulatory/resource information.
- punica granatum pericarp extract est-il sûr pour la peau de bébé ?
- No evidence of developmental toxicity in humans or harmonised classification. Mechanistic in vitro data (ER-modulation by pomegranate polyphenols) are relevant but do not demonstrate infant-specific harm. For infant (0–3 yr) skin, absorption can be higher than adults; therefore exposure is increased by one category compared with adults when measurable absorption cannot be excluded.
- Comment VeriMom évalue-t-il punica granatum pericarp extract ?
- VeriMom évalue punica granatum pericarp extract à 87/100 (risque faible) sur la base du statut EU CosIng, des classifications ECHA et des études PubMed.
- Quelles sont les alternatives sûres à punica granatum pericarp extract pendant la grossesse ?
- Consultez notre liste d'alternatives sûres à punica granatum pericarp extract basée sur une fonction similaire et une classification sans risques connus.
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Avis Médical
Ces informations sont fournies à titre éducatif uniquement et ne constituent pas un avis médical. Les scores de sécurité sont basés sur des données accessibles au public et peuvent ne pas refléter tous les risques. Consultez toujours votre professionnel de santé avant d'utiliser tout produit pendant la grossesse ou l'allaitement.