Is polysorbate 80 safe during pregnancy?
Polysorbate 80 (Tween 80, CAS 9005-65-6) has no harmonised reproductive classification in ECHA Annex VI, and the Cosmetic Ingredient Review (CIR) and related safety assessments find it safe as used in cosmetics; no credible evidence of human teratogenicity or reproductive hazard was identified in regulatory reviews or major dossiers.
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
polysorbate 80
NO KNOWN RISKS100
/100
0









Pregnancy-safe products containing polysorbate 80

A313
A313 Vitamin A Pommade (US Version)
100/100

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100/100

Colgate
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Givenchy
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Klorane Bébé
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blend-a-med
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ISOMERS Skincare
ISOMERS Skincare Accelerator Serum With Mosscelltec
99/100

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AZ
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Fluocaril
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Frequently asked questions
- Is polysorbate 80 safe during pregnancy?
- Polysorbate 80 (Tween 80, CAS 9005-65-6) has no harmonised reproductive classification in ECHA Annex VI, and the Cosmetic Ingredient Review (CIR) and related safety assessments find it safe as used in cosmetics; no credible evidence of human teratogenicity or reproductive hazard was identified in regulatory reviews or major dossiers.
- Is polysorbate 80 safe while breastfeeding?
- No regulatory or peer-reviewed evidence indicates reproductive or lactation-specific toxicity for polysorbate 80; no harmonised CLP reproductive hazard and CIR-type cosmetic safety conclusions support 'safe as used.' Systemic exposure from topical cosmetic use is negligible to low, so breastmilk transfer is not indicated in the safety assessments.
- Is polysorbate 80 safe for baby skin?
- No evidence of reproductive or developmental hazard specific to infants. Dermal exposure in infants is potentially higher due to immature barrier and higher surface-area-to-weight ratio; polysorbate 80 is not completely non-absorbable, so exposure score increased by +1 versus adult, but regulatory reviews (CIR, ECHA dossiers) do not identify infant-specific hazards.
- How does VeriMom score polysorbate 80?
- VeriMom scores polysorbate 80 at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to polysorbate 80?
- See our curated list of pregnancy-safe alternatives to polysorbate 80 based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.