Is polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate
NO KNOWN RISKS100
/100
0






Pregnancy-safe products containing polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate
uncategorized
NudeStix
Unknown Product
100/100

Chantecaille
Chantecaille Luster Glide Silk-Infused Eye Liner
100/100
sunscreen
NudeStix
Nude Earth - Coffret Stick Crayons Yeux - 6 x 2,5 g
100/100

Pure + Simple
Pure + Simple Nourishing Sunflower Cream
100/100
makeup
Pat McGrath Labs
Permagel Lip Pencil - Crayon à Lèvres - Night Fever (1,2 g)
100/100

Biolane
Liniment oléo-calcaire
99/100

Innisfree
innisfree Daily Soft Sunscreen Stick (SPF50+ Pa++++)
99/100

PAC
PAC Long-lasting Kohl Pencil
99/100

Huda Beauty
Huda Beauty Lip Contour
99/100

Ultrasun
Ultrasun 50SPF Mineral Baby
99/100
Related ingredients
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Sources & references
Authoritative references used to score this ingredient.
Frequently asked questions
- Is polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate safe during pregnancy?
- No harmonised CLP reproductive classification found (ECHA Annex VI), no CIR or SCCS safety assessment flagging reproductive hazard, and no peer‑reviewed reproductive or developmental toxicity data identified. The ingredient is a high‑molecular‑weight esterified lipid typically considered low systemic toxicity in cosmetic use (CosIng/ECHA general profiles).
- Is polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate safe while breastfeeding?
- No evidence from regulatory databases or peer‑reviewed literature of effects on lactation or transfer into breast milk; no harmonised classifications or CIR/SCCS restrictions identified. As a large esterified surfactant/emollient it is unlikely to pose specific lactation hazards at cosmetic topical exposures.
- Is polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate safe for baby skin?
- No data indicating reproductive or developmental hazard in infants. Topical exposure to this high‑molecular‑weight lipid is expected to have negligible systemic hazard (h=0, m=0) but infant skin has higher absorption potential; therefore exposure score is increased by +1 for babies (e=1) as a conservative adjustment in absence of infant‑specific absorption data.
- How does VeriMom score polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate?
- VeriMom scores polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate?
- See our curated list of pregnancy-safe alternatives to polyglyceryl-4 diisostearate/polyhydroxystearate/sebacate based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.