Is poloxamer 124 safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
poloxamer 124
NO KNOWN RISKS100
/100
0







Pregnancy-safe products containing poloxamer 124

Biotherm
Biotherm Biosource Cleansing Micellar Water
99/100
uncategorized
Unknown
deal worthy
98/100

La roche-posay
La Roche-Posay Soothing Toner
98/100

La roche-posay
La Roche-Posay Soothing Lotion For Sensitive Skin
98/100
face-masks
La roche-posay
La Roche-Posay Soothing Lotion 200ml
98/100

Plantnery
Plantnery Yuzu Orange Cleansing Water
98/100

Palmolive
gentle care mild fragrance
98/100

La roche-posay
Démaquillant yeux peaux sensibles
98/100

Palmolive
Essential Clean - Lemon Zest
97/100

Tactupump
Tactupump Forte
97/100
Related ingredients
See also
Sources & references
Authoritative references used to score this ingredient.
Frequently asked questions
- Is poloxamer 124 safe during pregnancy?
- The Cosmetic Ingredient Review (CIR) safety assessment (2008) evaluated many poloxamers including Poloxamer 124 and found no reproductive or developmental data but concluded 'safe as used' based on low skin penetration (high molecular weight, water‑soluble polymer) and rapid clearance when administered by other routes; no harmonised CLP classification for reproductive toxicity was found on ECHA. Therefore no reproductive hazard is identified. (CIR; ECHA substance info).
- Is poloxamer 124 safe while breastfeeding?
- No evidence of reproductive or developmental toxicity or mechanism suggesting transfer into breastmilk was identified in authoritative reviews. Poloxamers are large EO/PO block copolymers with minimal dermal absorption per the CIR assessment, so breastfeeding hazard is not indicated in available data (CIR; ECHA).
- Is poloxamer 124 safe for baby skin?
- Hazard and mechanism remain unsupported by data. Exposure score increased to 1 for infants (0–3 yr) because although adult dermal absorption is considered negligible/very low (CIR), infant skin has a higher surface‑area‑to‑weight ratio and immature barrier — so a small, measurable increase in exposure is plausible even if no toxicity is reported. No infant‑specific reproductive or developmental adverse findings were located.
- How does VeriMom score poloxamer 124?
- VeriMom scores poloxamer 124 at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to poloxamer 124?
- See our curated list of pregnancy-safe alternatives to poloxamer 124 based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.