VeriMomIs pentafluoropropane safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
pentafluoropropane
NO KNOWN RISKS100
/100
0
Pregnancy-safe products containing pentafluoropropane
ISOMERS Skincare
ISOMERS Skincare Oxygenforce 10 Min Mask
99/100
Auteur
Auteur Definitive Density Cream
98/100
Scinic
Scinic Sparkling Pore Cream
84/100
TonyMoly
TonyMoly Egg Pore Tightening Cooling Pack
82/100
Element Eight
Element Eight O2 Peptide Firm Perfect Cream
82/100
Cult51
Cult51 Derma Line Concentrate
82/100
Kilig
Kilig Urban Anti-Pollution Deep Clean Bubble Mask
78/100
Related ingredients
See also
Sources & references
Authoritative references used to score this ingredient.
Frequently asked questions
- Is pentafluoropropane safe during pregnancy?
- No harmonised CLP reproductive classification or SCCS/CIR safety assessment was found. Animal developmental studies report no teratogenic effects; a rat inhalation developmental study showed only a slight reduction in pup weight at very high exposures (50,000 ppm) but no developmental malformations, and human inhalation studies report very low systemic metabolism and low uptake (~2.1% relative uptake during exposure). Sources: Toxicol Sci (1999) developmental study; human uptake study (Toxicol Sci 2010); ECHA / EPA substance records. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/10630582/))
- Is pentafluoropropane safe while breastfeeding?
- No data indicate reproductive or lactation-specific toxicity or classification. Human toxicokinetic data show minimal metabolism and rapid elimination after inhalation exposure; no data show transfer into milk. No harmonised CLP reproductive hazard. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/19915083/))
- Is pentafluoropropane safe for baby skin?
- Pentafluoropropane (1,1,1,3,3‑pentafluoropropane, HFC‑245fa) is a volatile gas/liquid used industrially (e.g., blowing agent); there are no dermal reproductive or developmental hazard findings and dermal toxicity was not observed in available studies. Topical cosmetic use is not documented in authoritative cosmetic safety sources (no CIR or SCCS opinion or CosIng entry found), so topical exposure from cosmetics appears unlikely; available human studies address inhalation with low uptake. Therefore exposure from intended topical cosmetic use would be negligible. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/10630582/))
- How does VeriMom score pentafluoropropane?
- VeriMom scores pentafluoropropane at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to pentafluoropropane?
- See our curated list of pregnancy-safe alternatives to pentafluoropropane based on similar function and a no-known-risks safety band.
Check your own skincare
Paste any product's ingredient list into our free checker and see every ingredient scored against EU regulatory data and peer-reviewed research.
Open the pregnancy-safe ingredient checkerCheck every label in 2 seconds
Get VeriMom free — scan any product and see the pregnancy safety score instantly.
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.