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Is pentadecalactone safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
pentadecalactone
NO KNOWN RISKS
93
/100
0

Pregnancy-safe products containing pentadecalactone

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Authoritative references used to score this ingredient.

Frequently asked questions

Is pentadecalactone safe during pregnancy?
No harmonised CLP reproductive classifications (H360/H361) or SCCS/CIR reproductive safety assessments were found for pentadecalactone (CAS 106-02-5). A peer-reviewed RIFM fragrance ingredient safety assessment exists and does not identify reproductive/teratogenic hazards, and ECHA shows only company C&L notifications (not a harmonised classification). Topical cosmetic use is expected to give low but measurable dermal exposure for a lipophilic macrocyclic lactone. Sources: RIFM safety assessment (PubMed/ Food Chem Tox), ECHA substance/C&L entries, EWG ingredient page.
Is pentadecalactone safe while breastfeeding?
No data indicating reproductive or developmental hazards or mechanisms relevant to lactation were identified in authoritative reviews. Given lack of evidence for systemic reproductive toxicity and expected low dermal absorption from cosmetic use, exposure during breastfeeding is likely low but measurable; no evidence of transfer via milk was located.
Is pentadecalactone safe for baby skin?
No infant-specific reproductive/developmental hazards or mechanisms were identified. Because infant skin has higher surface-area-to-weight and an immature barrier, exposure score is increased by +1 relative to adults (adult e=1 → baby e=2). No infant dermal absorption studies were found.
How does VeriMom score pentadecalactone?
VeriMom scores pentadecalactone at 93/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to pentadecalactone?
See our curated list of pregnancy-safe alternatives to pentadecalactone based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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