VeriMomIs peg-45 bis-(tocopheryl succinate) safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
peg-45 bis-(tocopheryl succinate)
NO KNOWN RISKS100
/100
0
Pregnancy-safe products containing peg-45 bis-(tocopheryl succinate)
Facetheory
facetheory Lipabalm Bioactive Lip Balm Lp1
99/100
MixX laboratory
MixX laboratory Idebenone 1% Tightening Essence
98/100
BRTC
BRTC Panthenol 30 Barrier Ampoule
97/100
BRTC
BRTC Ph5.5 Vita Peeling Gel
97/100
Aizen
Aizen Holydrate Aqua Barrier Moisturizer
89/100
La mer
La Mer Crème De La Mer (Discontinued)
86/100
La Mer The Treatment Lotion - 15ml
86/100
La Mer The Treatment Lotion - 100ml
86/100
La Mer The Eye Balm Intense - 3ml (4ea) Set
86/100
La Mer The Eye Balm Intense - 3ml
86/100
Related ingredients
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Sources & references
Authoritative references used to score this ingredient.
Frequently asked questions
- Is peg-45 bis-(tocopheryl succinate) safe during pregnancy?
- No harmonised CLP reproductive classification (ECHA Annex VI) or SCCS/CIR finding indicating reproductive hazard for this ingredient class. Tocopherol derivatives (vitamin E and common esters) have CIR assessments supporting safety in cosmetics, and PEG polymers and tocopherols lack documented human teratogenicity in regulatory sources reviewed, so default no evidence of reproductive hazard. Sources: ECHA Annex VI (no harmonised H360/H361 entry), CIR (tocopherol family safety), PubChem/CosIng (no reproductive flags).
- Is peg-45 bis-(tocopheryl succinate) safe while breastfeeding?
- No regulatory or peer‑reviewed evidence that PEG-45 bis-(tocopheryl succinate) causes reproductive or lactation-related toxicity or that it is a known milk-borne toxin. Large PEGylated molecules typically have negligible dermal systemic uptake; tocopherol derivatives are not identified as lactation hazards in CIR/SCCS materials. Sources: CIR, PubChem, CosIng, ECHA (no harmonised classification).
- Is peg-45 bis-(tocopheryl succinate) safe for baby skin?
- No specific hazard or mechanism data for infants. Adult hazard/mechanism default to 0. Exposure score raised to 1 for baby skin because the ingredient is not an absolutely non‑absorbable inert particle (it is a PEGylated surfactant/ester), and infant skin has higher absorption/surface‑area‑to‑weight; however, absorption is still expected to be low for a high‑molecular‑weight PEG conjugate. Sources: general dermal absorption principles, CosIng/PubChem listings, CIR (tocopherol derivatives).
- How does VeriMom score peg-45 bis-(tocopheryl succinate)?
- VeriMom scores peg-45 bis-(tocopheryl succinate) at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to peg-45 bis-(tocopheryl succinate)?
- See our curated list of pregnancy-safe alternatives to peg-45 bis-(tocopheryl succinate) based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.