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Is hydroxypropyl cyclodextrin safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
hydroxypropyl cyclodextrin
NO KNOWN RISKS
100
/100
0

Pregnancy-safe products containing hydroxypropyl cyclodextrin

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Authoritative references used to score this ingredient.

Frequently asked questions

Is hydroxypropyl cyclodextrin safe during pregnancy?
No harmonised CLP classification (ECHA Annex VI) for reproductive toxicity, no SCCS or CIR reproductive warning, and available safety information for cyclodextrin derivatives indicates low systemic absorption and low toxicity (PubChem, ECHA dossiers). No animal or human reproductive/toxicology data indicating hazard were identified in authoritative sources.
Is hydroxypropyl cyclodextrin safe while breastfeeding?
Given negligible systemic absorption from topical cosmetic use and lack of reproductive toxicity flags or evidence of placental/mammary transfer, breastfeeding exposure is expected to be negligible. No authoritative source (ECHA Annex VI, SCCS, CIR) indicates a breastfeeding safety concern.
Is hydroxypropyl cyclodextrin safe for baby skin?
Hazard and mechanism: no evidence of reproductive or endocrine activity in authoritative sources. Exposure: topical absorption for adults is negligible; because infant skin barrier is immature, exposure score increased by +1 to reflect higher measurable absorption potential for 0–3 yr (principle applied per instructions). No infant-specific adverse data found.
How does VeriMom score hydroxypropyl cyclodextrin?
VeriMom scores hydroxypropyl cyclodextrin at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to hydroxypropyl cyclodextrin?
See our curated list of pregnancy-safe alternatives to hydroxypropyl cyclodextrin based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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