Is hydroxypropyl cyclodextrin safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
hydroxypropyl cyclodextrin
NO KNOWN RISKS100
/100
0









Pregnancy-safe products containing hydroxypropyl cyclodextrin

Rael
Rael Moisture Melt Snowball Hyaluronic Acid Concentrate
100/100

Satara
Satara Dead Sea Multi Vitamine Serum Anti Wrinkle
99/100

JorgObé
JorgObé Multi Peptide Lifting Filler
99/100

AlumierMD
AlumierMD Everactive C&E™ + Peptide
98/100

Axis-Y
AXIS-Y Dark Spot Correcting Glow Serum - 50ml (1ea) + Vegan Collagen Eye Serum - 10ml (1ea) Set
98/100

Fillerina
Fillerina Grad 2 Filler Treatment
98/100

IOMA
IOMA Ma Crème
98/100

NCN PRO SKINCARE
NCN PRO SKINCARE Multi-Active Peptide Matrixyl Serum 25%
98/100

Innisfree
innisfree Green Tea Caffeine Bright-Eye Serum
98/100

Somethinc
Somethinc Skin Defender Bakuchiol + Coq10 Serum
98/100
Related ingredients
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Sources & references
Authoritative references used to score this ingredient.
Frequently asked questions
- Is hydroxypropyl cyclodextrin safe during pregnancy?
- No harmonised CLP classification (ECHA Annex VI) for reproductive toxicity, no SCCS or CIR reproductive warning, and available safety information for cyclodextrin derivatives indicates low systemic absorption and low toxicity (PubChem, ECHA dossiers). No animal or human reproductive/toxicology data indicating hazard were identified in authoritative sources.
- Is hydroxypropyl cyclodextrin safe while breastfeeding?
- Given negligible systemic absorption from topical cosmetic use and lack of reproductive toxicity flags or evidence of placental/mammary transfer, breastfeeding exposure is expected to be negligible. No authoritative source (ECHA Annex VI, SCCS, CIR) indicates a breastfeeding safety concern.
- Is hydroxypropyl cyclodextrin safe for baby skin?
- Hazard and mechanism: no evidence of reproductive or endocrine activity in authoritative sources. Exposure: topical absorption for adults is negligible; because infant skin barrier is immature, exposure score increased by +1 to reflect higher measurable absorption potential for 0–3 yr (principle applied per instructions). No infant-specific adverse data found.
- How does VeriMom score hydroxypropyl cyclodextrin?
- VeriMom scores hydroxypropyl cyclodextrin at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to hydroxypropyl cyclodextrin?
- See our curated list of pregnancy-safe alternatives to hydroxypropyl cyclodextrin based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.