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Ist fisetin in der Schwangerschaft sicher?

No harmonised CLP (ECHA Annex VI) or SCCS/CIR reproductive/teratogenic classification for fisetin was identified in the authoritative sources searched; peer‑reviewed animal studies did not report teratogenicity and in some pregnancy models fisetin was protective (e.g., preeclampsia‑like rat model and mitigation of methylmercury developmental neurotoxicity). Some in vitro and in vivo work shows interaction with estrogen and androgen signalling (ER/AR modulation), but there is no evidence of a reproductive mechanism causing human/animal developmental toxicity. Given its molecular size and physicochemistry there is potential for low but measurable dermal absorption from topical use. Sources: PubMed studies and ECHA/C&L/SDS listings (self‑notifications exist in some supplier SDSs but these are not harmonised CLH and per your instruction do not raise hazard score).

Inhaltsstoffe
fisetin
KEINE BEKANNTEN RISIKEN
93
/100
0

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Frequently asked questions

Ist fisetin in der Schwangerschaft sicher?
No harmonised CLP (ECHA Annex VI) or SCCS/CIR reproductive/teratogenic classification for fisetin was identified in the authoritative sources searched; peer‑reviewed animal studies did not report teratogenicity and in some pregnancy models fisetin was protective (e.g., preeclampsia‑like rat model and mitigation of methylmercury developmental neurotoxicity). Some in vitro and in vivo work shows interaction with estrogen and androgen signalling (ER/AR modulation), but there is no evidence of a reproductive mechanism causing human/animal developmental toxicity. Given its molecular size and physicochemistry there is potential for low but measurable dermal absorption from topical use. Sources: PubMed studies and ECHA/C&L/SDS listings (self‑notifications exist in some supplier SDSs but these are not harmonised CLH and per your instruction do not raise hazard score).
Ist fisetin während des Stillens sicher?
No authoritative safety assessment (CIR or SCCS) or harmonised classification indicating harm to breastfed children was found. No controlled human data showing transfer into milk or adverse effects in suckling offspring; some animal pregnancy studies showed protective effects rather than toxicity. Dermal exposure from cosmetics would be expected to give low but measurable systemic exposure in adults, so a low exposure score is used. Self‑classified SDS statements claiming reproductive/breastfeeding hazard are present for some supplier documents but are not equivalent to harmonised CLH and were not used to increase the hazard score.
Ist fisetin sicher für Babyhaut?
No infant‑specific hazard evidence was identified. Per the scoring rules, because fisetin shows measurable dermal absorption in principle (small flavonol) the exposure score for baby skin is increased by +1 relative to adults to account for immature barrier and higher surface‑area‑to‑weight; there is no direct data showing increased hazard or infant‑specific mechanism, so hazard and mechanism scores remain at default.
Wie bewertet VeriMom fisetin?
VeriMom bewertet fisetin mit 93/100 (keine bekannten Risiken) basierend auf EU CosIng, ECHA-Klassifizierungen und PubMed-Studien.
Was sind schwangerschaftssichere Alternativen zu fisetin?
Siehe unsere kuratierte Liste der schwangerschaftssicheren Alternativen zu fisetin basierend auf ähnlicher Funktion.

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Medizinischer Haftungsausschluss

Diese Informationen dienen ausschließlich Bildungszwecken und stellen keine medizinische Beratung dar. Sicherheitsbewertungen basieren auf öffentlich zugänglichen Daten und spiegeln möglicherweise nicht alle Risiken wider. Konsultieren Sie immer Ihren Arzt, bevor Sie ein Produkt während der Schwangerschaft oder Stillzeit verwenden.

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