VeriMomIs deoxyribonuclease safe during pregnancy?
Reviewed by VeriMom Editorial Team · Last reviewed
Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
deoxyribonuclease
NO KNOWN RISKS100
/100
0
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Frequently asked questions
- Is deoxyribonuclease safe during pregnancy?
- Deoxyribonuclease (DNase I, CAS 9003-98-9) is a high–molecular-weight enzyme/protein used in biochemical and some cleaning/cosmetic formulations. I found no harmonised CLP reproductive classification (no H360/H361), no SCCS or CIR safety opinion specifically on this enzyme, and no peer‑reviewed evidence of reproductive or teratogenic effects from topical cosmetic use; therefore default hazard/mechanism/exposure scores are 0. Sources show ECHA substance/registration records and product listings but not harmonised repro flags. (ECHA substance info; ECHA registration docket; PubMed search showed DNase biology studies but not reproductive toxicity.).
- Is deoxyribonuclease safe while breastfeeding?
- No evidence that topical DNase I is a reproductive toxicant or that it transfers into breastmilk after cosmetic use. As a large protein enzyme with expected negligible dermal absorption in adults and no published data showing systemic lactational transfer from cosmetic exposure, exposure score is 0 and hazard/mechanism remain 0. (No CIR/SCCS/FDA classification found; ECHA entries are registrations/self‑notifications rather than harmonised CLP.).
- Is deoxyribonuclease safe for baby skin?
- No infant‑specific reproductive or developmental hazard data were found; hazard and mechanism remain 0. Exposure was rated 1 for baby skin because while adult topical absorption is expected negligible, infants have immature barrier and higher surface‑area/weight so small proteins with any measurable absorption get a +1 exposure uplift per the requested rules. No data show infant systemic uptake from cosmetic use. (ECHA product/registration listings; EWG ingredient page; lack of SCCS/CIR evaluations.).
- How does VeriMom score deoxyribonuclease?
- VeriMom scores deoxyribonuclease at 100/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
- What are pregnancy-safe alternatives to deoxyribonuclease?
- See our curated list of pregnancy-safe alternatives to deoxyribonuclease based on similar function and a no-known-risks safety band.
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Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.