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Is cocamidopropyl hydroxysultaine safe during pregnancy?

Reviewed by · Last reviewed

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
cocamidopropyl hydroxysultaine
NO KNOWN RISKS
93
/100
0

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Authoritative references used to score this ingredient.

Frequently asked questions

Is cocamidopropyl hydroxysultaine safe during pregnancy?
No harmonised reproductive classification or SCCS/CIR repro flag was identified. Repeated-dose/oral (OECD 422) studies reported a developmental/reproductive NOAEL around 300 mg/kg/day and agencies reviewing the data (registration dossiers / national assessments) concluded no developmental toxicity at doses ≤300 mg/kg/day, so there is no evidence of a reproductive hazard. For topical cosmetic use systemic absorption is expected to be low but measurable, so exposure is scored as low (e=1). Sources: ECHA registration dossier and national assessment. (ECHA OECD 422 dossier; Canada final assessment).
Is cocamidopropyl hydroxysultaine safe while breastfeeding?
No data indicating transfer to breastmilk or breastfeeding-specific adverse effects were found in authoritative dossiers or the published toxicology records. Animal studies show no reproductive/developmental hazard at relevant NOAELs; therefore hazard and mechanism scores are 0. Topical use implies low but measurable maternal systemic exposure, so breastfeeding exposure scored as low (e=1).
Is cocamidopropyl hydroxysultaine safe for baby skin?
No infant-specific reproductive/toxic mechanism or developmental evidence was found. Because the ingredient has measurable absorption in systemic toxicity studies (oral) and topical cosmetics can be absorbed to a low extent in adults, infant skin (0–3 yr) — which has an immature barrier and higher surface-area-to-weight ratio — receives one point higher exposure (adult e=1 → baby e=2). No infant-specific hazards were identified in the searched sources.
How does VeriMom score cocamidopropyl hydroxysultaine?
VeriMom scores cocamidopropyl hydroxysultaine at 93/100 (no known risks) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to cocamidopropyl hydroxysultaine?
See our curated list of pregnancy-safe alternatives to cocamidopropyl hydroxysultaine based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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