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Is chrysin safe during pregnancy?

Animal and in vitro studies report effects on ovarian function and estrogen receptor signalling (ERβ), indicating reproductive-related activity in non‑human models; no harmonised CLP (ECHA Annex VI), SCCS or CIR reproductive classification was identified, so this is suspected (not confirmed). Sources: PubMed animal study showing ERβ/ovarian effects and PubChem substance summary.

Pregnancy-Safe Ingredients Database — 28,000+ Ingredients Rated
chrysin
MEDIUM RISK
40
/100
0

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Frequently asked questions

Is chrysin safe during pregnancy?
Animal and in vitro studies report effects on ovarian function and estrogen receptor signalling (ERβ), indicating reproductive-related activity in non‑human models; no harmonised CLP (ECHA Annex VI), SCCS or CIR reproductive classification was identified, so this is suspected (not confirmed). Sources: PubMed animal study showing ERβ/ovarian effects and PubChem substance summary.
Is chrysin safe while breastfeeding?
Mechanistic and animal data (ER modulation; ovarian effects) raise a suspected reproductive/endocrine concern that could be relevant during lactation, but there are no human lactation/milk‑transfer data or regulatory harmonised classifications; exposure from topical cosmetic use is likely low but measurable.
Is chrysin safe for baby skin?
Same hazard/mechanism score as adults based on the animal/in vitro evidence; dermal exposure concern score increased for infants because baby skin has higher uptake per weight and immature barrier — dermal absorption data for chrysin are lacking but the chemical is a small lipophilic flavone so measurable absorption is plausible, so exposure is increased by +1 for 0–3 yr.
How does VeriMom score chrysin?
VeriMom scores chrysin at 40/100 (medium risk) based on EU CosIng status, ECHA hazard classifications, and peer-reviewed PubMed studies. Our scoring pipeline is fully transparent.
What are pregnancy-safe alternatives to chrysin?
See our curated list of pregnancy-safe alternatives to chrysin based on similar function and a no-known-risks safety band.

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Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice. Safety scores are based on publicly available data and may not reflect all risks. Always consult your healthcare provider before using any product during pregnancy or breastfeeding.

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