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beta-sitosterol은 임신 중 안전한가요?

CIR reviews of phytosterols note general cosmetic safety but some animal data show reproductive/embryotoxic effects at high or non-oral exposures; recent peer‑reviewed animal studies (mink, rodents, and a 2024 mouse study) report effects on reproductive endpoints, and beta‑sitosterol has demonstrated phytoestrogen/sex‑hormone‑modulating activity—so reproductive hazard is suspected (h=2) with a demonstrated mechanism (m=2). Topical cosmetic use gives low but measurable systemic exposure (e=1), much lower than doses in the animal studies; no harmonised CLP (ECHA Annex VI) classification was found. Sources: CIR phytosterol assessment; mink and rodent reproductive studies; recent 2024 mouse study; ECHA registration absence of harmonised classification.

성분
beta-sitosterol
중간 위험
40
/100
0

임신 중 beta-sitosterol 대체 안전 성분 | VeriMom

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Frequently asked questions

beta-sitosterol은 임신 중 안전한가요?
CIR reviews of phytosterols note general cosmetic safety but some animal data show reproductive/embryotoxic effects at high or non-oral exposures; recent peer‑reviewed animal studies (mink, rodents, and a 2024 mouse study) report effects on reproductive endpoints, and beta‑sitosterol has demonstrated phytoestrogen/sex‑hormone‑modulating activity—so reproductive hazard is suspected (h=2) with a demonstrated mechanism (m=2). Topical cosmetic use gives low but measurable systemic exposure (e=1), much lower than doses in the animal studies; no harmonised CLP (ECHA Annex VI) classification was found. Sources: CIR phytosterol assessment; mink and rodent reproductive studies; recent 2024 mouse study; ECHA registration absence of harmonised classification.
beta-sitosterol은 모유 수유 중 안전한가요?
Same rationale as pregnancy: animal evidence of reproductive effects and demonstrated hormone/immune modulation suggest suspected hazard (h=2) with a demonstrated mechanism (m=2). Systemic transfer to milk after topical cosmetic use is expected to be low but measurable (e=1)—clinical human lactation transfer data are lacking.
beta-sitosterol은 아기 피부에 안전한가요?
No infant‑specific data showing reproductive or developmental toxicity from topical exposure; per instructions we do not increase hazard/mechanistic scores without infant‑specific evidence (h=0,m=0). Beta‑sitosterol is lipophilic with measurable but limited dermal absorption in adults (adult e≈1), and immature infant skin increases exposure — therefore exposure for baby skin is raised by +1 to e=2 (low→moderate). CIR and CosIng list beta‑sitosterol for topical use with no specific concentration restrictions in cosmetics.
VeriMom은 beta-sitosterol을 어떻게 평가하나요?
VeriMom은 EU CosIng, ECHA 분류, PubMed 연구를 기반으로 beta-sitosterol을 40/100 (중간 위험)로 평가합니다.
임신 중 beta-sitosterol 대체 안전 성분은?
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