Безопасен ли isopropylidenediphenol diglycidyl ether при беременности?
ECHA Annex VI (harmonised CLP) assigns H315, H319, H317 (skin/eye irritation and skin sensitisation) to this substance (listed as bis-[4-(2,3-epoxipropoxi)phenyl]propane) but does NOT include any reproductive classifications (H360/H361). There are no authoritative reproductive/toxicology classifications cited for this substance; however, the chemical is a diglycidyl ether of a bisphenol-type scaffold which gives a theoretical (structural) concern for endocrine activity (mechanism=1) but no direct reproductive data to raise hazard (h=0). Estimated dermal systemic exposure from cosmetic topical use is low but measurable (e=1) based on its use as an epoxy-diglycidyl ether and skin reactivity (H317). Sources: ECHA Annex VI (harmonised CLP), ECHA H-codes.
Related ingredients
Frequently asked questions
- Безопасен ли isopropylidenediphenol diglycidyl ether при беременности?
- ECHA Annex VI (harmonised CLP) assigns H315, H319, H317 (skin/eye irritation and skin sensitisation) to this substance (listed as bis-[4-(2,3-epoxipropoxi)phenyl]propane) but does NOT include any reproductive classifications (H360/H361). There are no authoritative reproductive/toxicology classifications cited for this substance; however, the chemical is a diglycidyl ether of a bisphenol-type scaffold which gives a theoretical (structural) concern for endocrine activity (mechanism=1) but no direct reproductive data to raise hazard (h=0). Estimated dermal systemic exposure from cosmetic topical use is low but measurable (e=1) based on its use as an epoxy-diglycidyl ether and skin reactivity (H317). Sources: ECHA Annex VI (harmonised CLP), ECHA H-codes.
- Безопасен ли isopropylidenediphenol diglycidyl ether при грудном вскармливании?
- No reproductive or lactation-specific toxicology or human data identified in the authoritative regulatory classification. Theoretical structural concern exists because the molecule is a bisphenol-derived diglycidyl ether (mechanism=1) but there is no direct evidence of transfer into milk or lactation toxicity (h=0). Systemic exposure after dermal cosmetic use is expected low but measurable (e=1). Sources: ECHA Annex VI (harmonised CLP), ECHA H-codes.
- Безопасен ли isopropylidenediphenol diglycidyl ether для кожи малыша?
- Harmonised ECHA classification addresses skin irritation, eye irritation and sensitisation only; no harmonised reproductive or developmental hazard is assigned (h=0). Mechanistic concern remains theoretical due to the bisphenol-type structure (m=1). Dermal exposure potential is higher in infants because of thinner barrier and higher surface area-to-body-weight; therefore exposure score is increased by +1 compared with adults (adult e=1 → infant e=2). No infant-specific toxicokinetic or safety studies were identified. Sources: ECHA Annex VI (harmonised CLP), ECHA H-codes.
- Как VeriMom оценивает isopropylidenediphenol diglycidyl ether?
- VeriMom оценивает isopropylidenediphenol diglycidyl ether в 87/100 (низкий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы isopropylidenediphenol diglycidyl ether при беременности?
- См. наш список безопасных альтернатив isopropylidenediphenol diglycidyl ether с аналогичной функцией и классификацией без известных рисков.
Проверь любой состав за 2 секунды
Скачай VeriMom бесплатно — отсканируй любой продукт и мгновенно получи оценку безопасности при беременности.
Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.