VeriMomБезопасен ли dioscorea oppositifolia root extract при беременности?
No harmonised CLP reproductive classification (ECHA Annex VI) or CIR/SCCS safety assessment specific to Dioscorea oppositifolia root extract was found, and regulatory sources do not flag it as a reproductive teratogen — so default hazard = 0. However, the presence of steroidal sapogenins such as diosgenin in Dioscorea species provides a theoretical structural/class-based concern for endocrine activity based on in vitro/chemical similarity data (PubMed), so mechanism = 1. For typical topical cosmetic use, systemic exposure is expected to be low but measurable, so exposure = 1.
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Frequently asked questions
- Безопасен ли dioscorea oppositifolia root extract при беременности?
- No harmonised CLP reproductive classification (ECHA Annex VI) or CIR/SCCS safety assessment specific to Dioscorea oppositifolia root extract was found, and regulatory sources do not flag it as a reproductive teratogen — so default hazard = 0. However, the presence of steroidal sapogenins such as diosgenin in Dioscorea species provides a theoretical structural/class-based concern for endocrine activity based on in vitro/chemical similarity data (PubMed), so mechanism = 1. For typical topical cosmetic use, systemic exposure is expected to be low but measurable, so exposure = 1.
- Безопасен ли dioscorea oppositifolia root extract при грудном вскармливании?
- No authoritative reports (ECHA Annex VI, CIR, SCCS) identify lactation or breastmilk transfer hazards for this extract, so hazard = 0. Theoretical endocrine-related mechanism from diosgenin-containing extracts supports a low-level mechanistic concern (m=1). Topical use would likely result in low maternal systemic exposure and therefore low risk of transfer to breastmilk (e=1).
- Безопасен ли dioscorea oppositifolia root extract для кожи малыша?
- There is no evidence of infant-specific reproductive or developmental toxicity in authoritative sources for this extract (h=0). Mechanistic/theoretical concerns about steroidal saponins remain (m=1) but are not demonstrated in vivo. Because infant skin has higher per-body-weight absorption, exposure is increased by +1 relative to adults (adult e=1 → baby e=2), making dermal exposure potentially more relevant for 0–3 yr olds.
- Как VeriMom оценивает dioscorea oppositifolia root extract?
- VeriMom оценивает dioscorea oppositifolia root extract в 87/100 (низкий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы dioscorea oppositifolia root extract при беременности?
- См. наш список безопасных альтернатив dioscorea oppositifolia root extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.