Безопасен ли diethylhexyl sodium sulfosuccinate при беременности?
No EU harmonised CLP classification (Annex VI) for reproductive toxicity was located; some supplier SDS/C&L notifications list H361/H362 but these appear to be company self‑classifications, not an EU harmonised CLH. Regulatory and expert reviews (JECFA, CIR, CosmeticsInfo) indicate available animal reproductive data with a reported NOEL (50 mg/kg in rat reproductive study) but no harmonised classification or consistent evidence of human teratogenicity — hence a low-level concern (h=1). Dermal exposure from cosmetics is expected to give low but measurable systemic exposure. Sources: ECHA substance page and C&L notifications; JECFA evaluation; CIR re-review; CosmeticsInfo review.
Безопасные альтернативы diethylhexyl sodium sulfosuccinate при беременности | VeriMom
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- Безопасен ли diethylhexyl sodium sulfosuccinate при беременности?
- No EU harmonised CLP classification (Annex VI) for reproductive toxicity was located; some supplier SDS/C&L notifications list H361/H362 but these appear to be company self‑classifications, not an EU harmonised CLH. Regulatory and expert reviews (JECFA, CIR, CosmeticsInfo) indicate available animal reproductive data with a reported NOEL (50 mg/kg in rat reproductive study) but no harmonised classification or consistent evidence of human teratogenicity — hence a low-level concern (h=1). Dermal exposure from cosmetics is expected to give low but measurable systemic exposure. Sources: ECHA substance page and C&L notifications; JECFA evaluation; CIR re-review; CosmeticsInfo review.
- Безопасен ли diethylhexyl sodium sulfosuccinate при грудном вскармливании?
- Same rationale as pregnancy: no harmonised H360/H361 in Annex VI; animal reproductive data exist (JECFA referenced reproductive NOEL) but not sufficient to classify as suspected/confirmed reproductive toxicant at cosmetic exposure levels. Predicted dermal absorption from cosmetic use is low but measurable, so breastfeeding is assigned the same hazard (h=1) and low exposure (e=1). No specific data on milk transfer were found in searched databases.
- Безопасен ли diethylhexyl sodium sulfosuccinate для кожи малыша?
- Ingredient is a surfactant (anionic, water‑soluble). Reviews (CIR and CosmeticsInfo) consider dialkyl sulfosuccinates as a group for cosmetics; no infant‑specific developmental toxicity via dermal route was identified. Because infant skin has higher surface‑area‑to‑weight and a less mature barrier, exposure score is increased by +1 (adult e=1 → infant e=2). Hazard remains low (h=1) absent infant‑specific adverse evidence.
- Как VeriMom оценивает diethylhexyl sodium sulfosuccinate?
- VeriMom оценивает diethylhexyl sodium sulfosuccinate в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы diethylhexyl sodium sulfosuccinate при беременности?
- См. наш список безопасных альтернатив diethylhexyl sodium sulfosuccinate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.