VeriMomСтоит ли избегать zinc pyrithione при беременности? | VeriMom
Zinc pyrithione (CAS 13463-41-7) has a harmonised CLP classification including H360D (may damage the unborn child) recorded by ECHA - which mandates high hazard (h=3). Animal and embryonic models (e.g., zebrafish developmental toxicity and mechanistic studies showing oxidative damage, apoptosis and developmental gene changes) provide demonstrated mechanisms of developmental toxicity (m=2). Topical cosmetic exposure is measurable but generally limited for rinse‑off products (SCCS evaluated consumer exposure when concluding on safety), so exposure for pregnant adults is scored as low but measurable (e=1). Sources: ECHA harmonised classification / regulatory texts, SCCS opinion (2020), peer‑reviewed developmental/toxicogenomic studies.
ECHA regulatory hazard statements
- •H360D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли zinc pyrithione при беременности?
- Zinc pyrithione (CAS 13463-41-7) has a harmonised CLP classification including H360D (may damage the unborn child) recorded by ECHA - which mandates high hazard (h=3). Animal and embryonic models (e.g., zebrafish developmental toxicity and mechanistic studies showing oxidative damage, apoptosis and developmental gene changes) provide demonstrated mechanisms of developmental toxicity (m=2). Topical cosmetic exposure is measurable but generally limited for rinse‑off products (SCCS evaluated consumer exposure when concluding on safety), so exposure for pregnant adults is scored as low but measurable (e=1). Sources: ECHA harmonised classification / regulatory texts, SCCS opinion (2020), peer‑reviewed developmental/toxicogenomic studies.
- Безопасен ли zinc pyrithione при грудном вскармливании?
- Harmonised CLP H360D and the EU regulatory action place zinc pyrithione as a reproductive toxicant (h=3). Mechanistic and animal/developmental data (see PubMed studies) support demonstrated developmental toxicity pathways (m=2). Breastfeeding exposure from typical topical cosmetic rinse‑off use is likely low but measurable (e=1); direct data on transfer into human milk are lacking, so exposure is conservatively scored as low but measurable.
- Безопасен ли zinc pyrithione для кожи малыша?
- The substance carries harmonised H360D (h=3). Mechanistic/developmental toxicity evidence from animal/embryo studies supports demonstrated mechanisms (m=2). Per your guidance, infant exposure is increased by +1 relative to adults because infant skin has higher absorption / surface‑area‑to‑weight; with adult cosmetic exposure scored as measurable, infant exposure is scored as moderate (e=2). There are no infant‑specific safety data showing safety.
- Как VeriMom оценивает zinc pyrithione?
- VeriMom оценивает zinc pyrithione в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы zinc pyrithione при беременности?
- См. наш список безопасных альтернатив zinc pyrithione с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.