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Стоит ли избегать trimethylolpropane triacrylate при беременности? | VeriMom

ECHA/RAC has issued an opinion leading to a harmonised classification for trimethylolpropane triacrylate (TMPTA; CAS 15625-89-5) as a reproductive toxicant (H360 category 1B, e.g. H360D in proposals), which places it at the highest hazard score. Animal toxicology studies report systemic/dermal toxicity findings consistent with reproductive/developmental concerns. Dermal exposure from cosmetics is therefore a measurable exposure route but not expected to give very high bioavailability in typical topical use. (ECHA harmonised CLH opinion; NTP/PubMed dermal toxicology studies).

ECHA regulatory hazard statements

  • H351

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли trimethylolpropane triacrylate при беременности?
ECHA/RAC has issued an opinion leading to a harmonised classification for trimethylolpropane triacrylate (TMPTA; CAS 15625-89-5) as a reproductive toxicant (H360 category 1B, e.g. H360D in proposals), which places it at the highest hazard score. Animal toxicology studies report systemic/dermal toxicity findings consistent with reproductive/developmental concerns. Dermal exposure from cosmetics is therefore a measurable exposure route but not expected to give very high bioavailability in typical topical use. (ECHA harmonised CLH opinion; NTP/PubMed dermal toxicology studies).
Безопасен ли trimethylolpropane triacrylate при грудном вскармливании?
Because TMPTA has a harmonised H360 reproductive classification (presumed to damage the unborn child) and animal reproductive/developmental effects have been reported, the reproductive hazard applies to lactation contexts as well. Breastfeeding exposure would depend on maternal systemic uptake; for typical topical cosmetic use systemic uptake is expected to be low but measurable, so infant exposure via breastmilk cannot be excluded. (ECHA CLH opinion; dermal toxicology data).
Безопасен ли trimethylolpropane triacrylate для кожи малыша?
The same harmonised reproductive hazard (H360, Category 1B) applies as the intrinsic hazard is confirmed by ECHA/RAC and animal data. Skin exposure for infants (0–3 yr) should be scored higher for exposure because infant skin has higher surface-area-to-weight and an immature barrier; therefore exposure is increased by one band relative to adults when dermal absorption is measurable. TMPTA is a reactive acrylate monomer with known dermal effects and measurable absorption in toxicology studies. (ECHA CLH/opinion; dermal toxicology studies; EWG listing).
Как VeriMom оценивает trimethylolpropane triacrylate?
VeriMom оценивает trimethylolpropane triacrylate в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы trimethylolpropane triacrylate при беременности?
См. наш список безопасных альтернатив trimethylolpropane triacrylate с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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