Стоит ли избегать trimethylbenzoyl diphenylphosphine oxide при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли trimethylbenzoyl diphenylphosphine oxide при беременности?

Diphenyl(2,4,6‑trimethylbenzoyl)phosphine oxide (TPO) has a harmonised CLP classification Repr. 1B, H360Fd (may damage fertility; suspected of damaging the unborn child), which by calibration dictates h=3. Animal/reproductive data and regulatory assessments document reproductive/developmental effects (supporting a demonstrated mechanism), while dermal exposure from cosmetic nail use is low but measurable. ([echa.europa.eu](https://echa.europa.eu/web/guest/brief-profile/-/briefprofile/100.071.211?utm_source=openai))

Безопасен ли trimethylbenzoyl diphenylphosphine oxide при грудном вскармливании?

Because the substance carries a harmonised Repr. 1B (H360Fd) classification, it is scored h=3 for breastfeeding context as well (harmonised CMR classifications indicate confirmed concern independent of route). Mechanistic support comes from animal reproductive/developmental findings noted in dossiers and assessments. Typical topical use (nail products) gives low but measurable dermal exposure; specific transfer into breast milk is not documented in public dossiers. ([echa.europa.eu](https://echa.europa.eu/web/guest/brief-profile/-/briefprofile/100.071.211?utm_source=openai))

Безопасен ли trimethylbenzoyl diphenylphosphine oxide для кожи малыша?

Harmonised Repr.1B (H360Fd) sets h=3 for infants when considering potential harm; mechanism supported by animal reproductive/toxicology findings. Dermal exposure for baby skin is increased relative to adults because infant skin has higher permeability and surface‑area‑to‑weight; therefore exposure score is adult+1 (1→2) given measurable dermal absorption from cosmetic use and absence of evidence showing zero absorption. No infant‑specific dermal toxicokinetic studies were found. ([echa.europa.eu](https://echa.europa.eu/web/guest/brief-profile/-/briefprofile/100.071.211?utm_source=openai))

Как VeriMom оценивает trimethylbenzoyl diphenylphosphine oxide?

VeriMom оценивает trimethylbenzoyl diphenylphosphine oxide в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы trimethylbenzoyl diphenylphosphine oxide при беременности?

См. наш список безопасных альтернатив trimethylbenzoyl diphenylphosphine oxide с аналогичной функцией и классификацией без известных рисков.