Стоит ли избегать thiourea при беременности? | VeriMom
Thiourea is listed with a harmonised reproductive/developmental hazard (H361d — 'suspected of damaging the unborn child') by EU sources, and experimental studies show it inhibits thyroid hormone synthesis (antithyroid action) which can cause developmental effects in animals; this provides a suspected reproductive hazard and a demonstrated mechanism (thyroid inhibition). Topical cosmetic use would likely give low but measurable systemic exposure (no dermal absorption data specific to cosmetic formulations found). ([echa.europa.eu](https://echa.europa.eu/documents/10162/8cf0cdee-7849-4008-99d7-d4cc17706614?utm_source=openai))
ECHA regulatory hazard statements
- •H351
- •H361D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли thiourea при беременности?
- Thiourea is listed with a harmonised reproductive/developmental hazard (H361d — 'suspected of damaging the unborn child') by EU sources, and experimental studies show it inhibits thyroid hormone synthesis (antithyroid action) which can cause developmental effects in animals; this provides a suspected reproductive hazard and a demonstrated mechanism (thyroid inhibition). Topical cosmetic use would likely give low but measurable systemic exposure (no dermal absorption data specific to cosmetic formulations found). ([echa.europa.eu](https://echa.europa.eu/documents/10162/8cf0cdee-7849-4008-99d7-d4cc17706614?utm_source=openai))
- Безопасен ли thiourea при грудном вскармливании?
- Hazard and mechanism mirror pregnancy: harmonised H361d and demonstrated antithyroid activity in animals. There are no robust data on transfer of thiourea into human milk after topical exposure, so breastfeeding exposure is judged low but potentially measurable from systemic absorption; the developmental risk pathway (maternal hypothyroidism or direct exposure) remains plausible based on animal and mechanistic data. ([echa.europa.eu](https://echa.europa.eu/documents/10162/8cf0cdee-7849-4008-99d7-d4cc17706614?utm_source=openai))
- Безопасен ли thiourea для кожи малыша?
- The same suspected developmental hazard (H361d) and demonstrated antithyroid mechanism apply. For baby (0–3 yr) skin, exposure score is increased by +1 because infant skin is more permeable and surface-area-to-body-weight higher; given measurable dermal absorption in adults is plausible, infant exposure is assessed as moderate. No infant-specific toxicokinetic or dermal absorption studies were located. ([echa.europa.eu](https://echa.europa.eu/documents/10162/8cf0cdee-7849-4008-99d7-d4cc17706614?utm_source=openai))
- Как VeriMom оценивает thiourea?
- VeriMom оценивает thiourea в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы thiourea при беременности?
- См. наш список безопасных альтернатив thiourea с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.