VeriMomСтоит ли избегать tetrahydrofurfuryl alcohol при беременности? | VeriMom
ECHA lists tetrahydrofurfuryl alcohol (CAS 97-99-4) with a harmonised classification Repr. 1B H360Df (may damage the unborn child), which is legally binding in the EU and justifies a Category 1 CMR hazard (h=3). Reproductive/developmental effects are reported in an OECD-style rat screening study (reduced pups, resorptions, effects on parental reproductive organs; NOAELs reported), supporting demonstrated in vivo developmental toxicity (m=2). For typical topical cosmetic use systemic absorption is possible but not expected to be high; therefore exposure for a cosmetic user is scored as low-to-measurable (e=1). Sources: ECHA harmonised classification and rat reproduction screening study.
ECHA regulatory hazard statements
- •H360DF
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Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли tetrahydrofurfuryl alcohol при беременности?
- ECHA lists tetrahydrofurfuryl alcohol (CAS 97-99-4) with a harmonised classification Repr. 1B H360Df (may damage the unborn child), which is legally binding in the EU and justifies a Category 1 CMR hazard (h=3). Reproductive/developmental effects are reported in an OECD-style rat screening study (reduced pups, resorptions, effects on parental reproductive organs; NOAELs reported), supporting demonstrated in vivo developmental toxicity (m=2). For typical topical cosmetic use systemic absorption is possible but not expected to be high; therefore exposure for a cosmetic user is scored as low-to-measurable (e=1). Sources: ECHA harmonised classification and rat reproduction screening study.
- Безопасен ли tetrahydrofurfuryl alcohol при грудном вскармливании?
- Harmonised Repr. 1B (H360Df) applies irrespective of exposure route and therefore indicates a high hazard for lactating people (h=3). Mechanistic evidence is from in vivo reproductive/developmental findings in animals (m=2). There are no high-quality lactation-transfer data; for typical cosmetic topical use systemic exposure is likely low-to-measurable (e=1), but if significant systemic exposure occurs transfer to milk cannot be ruled out.
- Безопасен ли tetrahydrofurfuryl alcohol для кожи малыша?
- Hazard remains high (h=3) because of the harmonised H360Df classification. Mechanistic rating is based on demonstrated in vivo developmental/reproductive effects in animals (m=2). Exposure for infants 0–3 years is increased by one point per your instructions because of immature barrier and higher SA:BW; therefore e is increased to 2 (moderate exposure potential) even if adult topical exposure would be low.
- Как VeriMom оценивает tetrahydrofurfuryl alcohol?
- VeriMom оценивает tetrahydrofurfuryl alcohol в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы tetrahydrofurfuryl alcohol при беременности?
- См. наш список безопасных альтернатив tetrahydrofurfuryl alcohol с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.