Стоит ли избегать sulindac при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

Pregnancy-safe products to use instead

Products built around the safer ingredients above, scored "no known risks" or "low risk".

L'Occitane

100

L´Occitane Powder To-mousse Facial Exfoliator

Mew mew tweet

100

Mew mew tweet Cedar Spruce Baking Soda Free

Unknown

100

schmidts here now

Sustain Yourself

100

Sustain Yourself Natural Deodorant

Bitamin

100

Bitamin Natural Deodorant N'orange

Avero

100

Avero Solid Deodorant

Gilette

99

Gilette Intimate Anti-chafing Stick

Dr Teals's

99

Dr Teals's Aluminum Free Deodorant Charcoal

HappySoaps

99

Happysoaps Neutraal

900care

99

Déodorant stick parfum embruns

Безопасные альтернативы sulindac при беременности | VeriMom

Ингредиенты — Ингредиенты

См. также

• Безопасен ли sulindac при беременности?
• Безопасен ли sulindac для малышей?
• Какие безопасные при беременности альтернативы sulindac?

FAQ

Безопасен ли sulindac при беременности?

Sulindac is an NSAID with human and animal evidence of fetal harm (e.g., fetal renal dysfunction/oligohydramnios and ductus arteriosus effects that are class warnings for NSAIDs) and is listed by some safety sources as suspected/known developmental hazard; therefore reproductive hazard is suspected (H361 level evidence from registrants/SDSs and clinical reports). Mechanism is demonstrated COX/prostaglandin inhibition with known placental/fetal effects. Topical cosmetic use would give negligible systemic exposure compared with oral dosing; therefore exposure from a cosmetic topical route is judged negligible for adults. (Sources: LactMed (NLM), StatPearls/NCBI review of NSAIDs in pregnancy, clinical/toxicology studies; SDSs listing H361).

Безопасен ли sulindac при грудном вскармливании?

Breastfeeding guidance (LactMed) advises avoidance or preference for alternatives because data are lacking and sulindac has a long half‑life and metabolites; systemic maternal exposure can transfer drug/metabolites to milk. Mechanism (COX inhibition/systemic distribution) is established. Topical cosmetic use would be expected to give negligible maternal systemic exposure, so direct exposure via milk from cosmetic use is expected to be negligible. (Sources: LactMed, NCBI reviews, SDSs).

Безопасен ли sulindac для кожи малыша?

No infant‑specific dermal toxicity data were found. Hazard and mechanism remain the same (suspected reproductive/developmental hazard via prostaglandin inhibition). For baby skin (0–3 yr) exposure score is increased by +1 relative to adult because infant skin barrier is immature and systemic absorption may be greater if measurable; although topical cosmetic use of sulindac is uncommon and absolute absorption is likely low, infant exposure via dermal application cannot be assumed negligible without formulation data. (Sources: LactMed, NCBI/StatPearls on NSAIDs; SDSs/EHS listings).

Как VeriMom оценивает sulindac?

VeriMom оценивает sulindac в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы sulindac при беременности?

См. наш список безопасных альтернатив sulindac с аналогичной функцией и классификацией без известных рисков.