Стоит ли избегать styrene при беременности? | VeriMom
Styrene has a harmonised CLP reproduction hazard classification H361d (suspected of damaging fertility or the unborn child) under ECHA/CLP (legally binding), which supports h=2. Animal inhalation studies report developmental/neurobehavioral effects at high exposures and styrene is metabolised to styrene oxide (a reactive metabolite) — a demonstrated mechanistic route relevant to toxicity, so m=2. For normal topical cosmetic use dermal exposure and bioavailability are expected to be low, so e=1 for pregnancy (measurable but low). Sources: ECHA substance & CLH information, NTP/OHAT and peer-reviewed reviews.
ECHA regulatory hazard statements
- •H361D
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли styrene при беременности?
- Styrene has a harmonised CLP reproduction hazard classification H361d (suspected of damaging fertility or the unborn child) under ECHA/CLP (legally binding), which supports h=2. Animal inhalation studies report developmental/neurobehavioral effects at high exposures and styrene is metabolised to styrene oxide (a reactive metabolite) — a demonstrated mechanistic route relevant to toxicity, so m=2. For normal topical cosmetic use dermal exposure and bioavailability are expected to be low, so e=1 for pregnancy (measurable but low). Sources: ECHA substance & CLH information, NTP/OHAT and peer-reviewed reviews.
- Безопасен ли styrene при грудном вскармливании?
- Harmonised CLP H361d applies equally for reproductive hazard including risk to the unborn and supports an elevated hazard for lactation contexts (h=2). Metabolism to styrene oxide and systemic effects following inhalation/other exposures are documented (m=2). Typical cosmetic topical use would give low but measurable systemic exposure (e=1); milk transfer is possible at sufficient systemic levels but specific human lactation data are limited.
- Безопасен ли styrene для кожи малыша?
- Hazard remains h=2 because of the harmonised H361d classification and animal reproductive findings. Mechanistic concerns (metabolism to styrene oxide) remain relevant (m=2). Exposure score increased by +1 for infants (user rule) because baby skin has higher absorption and a higher surface-area-to-weight ratio; if adult e=1 then infant e=2. There is limited direct infant-specific data.
- Как VeriMom оценивает styrene?
- VeriMom оценивает styrene в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы styrene при беременности?
- См. наш список безопасных альтернатив styrene с аналогичной функцией и классификацией без известных рисков.
Проверь любой состав за 2 секунды
Скачай VeriMom бесплатно — отсканируй любой продукт и мгновенно получи оценку безопасности при беременности.
Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.