Стоит ли избегать silybum marianum fruit extract при беременности? | VeriMom
No EU harmonised classification (CLH) for CAS 84604-20-6 was identified on ECHA substance pages, though some supplier SDS for concentrated silymarin list H361 (self-classified). Peer-reviewed animal studies and reviews report no clear reproductive/developmental toxicity and in some cases protective effects of silymarin. Given the lack of harmonised H360/H361 CLH and the presence of supplier H361 self-classifications, hazard is scored as 1 (class/structural concern/self-notifications noted). (Sources: ECHA substance/registration pages; supplier SDS; PubMed review and animal study).
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли silybum marianum fruit extract при беременности?
- No EU harmonised classification (CLH) for CAS 84604-20-6 was identified on ECHA substance pages, though some supplier SDS for concentrated silymarin list H361 (self-classified). Peer-reviewed animal studies and reviews report no clear reproductive/developmental toxicity and in some cases protective effects of silymarin. Given the lack of harmonised H360/H361 CLH and the presence of supplier H361 self-classifications, hazard is scored as 1 (class/structural concern/self-notifications noted). (Sources: ECHA substance/registration pages; supplier SDS; PubMed review and animal study).
- Безопасен ли silybum marianum fruit extract при грудном вскармливании?
- Same rationale as pregnancy: no harmonised CLH; limited animal data do not show developmental harm and may indicate protective effects. Topical cosmetic use would give low systemic exposure for the lactating parent, so breastfeeding hazard scored 1 (precaution due to self-classed H361 on some SDS and active flavonolignan content).
- Безопасен ли silybum marianum fruit extract для кожи малыша?
- Ingredient is a botanical extract (skin-conditioning/antioxidant). Adult topical absorption is expected to be low; however per instruction baby exposure score is increased by +1 because infant skin barrier is immature. No infant-specific toxicity data were found. Therefore hazard/mechanism same as adult (1), exposure increased to 2 for 0–3 y/o. (Sources: CosIng listings, EWG Skin Deep, PubMed literature).
- Как VeriMom оценивает silybum marianum fruit extract?
- VeriMom оценивает silybum marianum fruit extract в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы silybum marianum fruit extract при беременности?
- См. наш список безопасных альтернатив silybum marianum fruit extract с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.