Стоит ли избегать retinyl palmitate при беременности? | VeriMom

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли retinyl palmitate при беременности?

Retinyl palmitate is associated with developmental/teratogenic effects in animal oral studies (rats/rabbits) and is a source of retinoic acid activity; this supports a 'suspected' reproductive hazard rather than a harmonised Category 1 human teratogen classification. The mechanistic basis is well characterized (retinoid → retinoic acid, RAR agonism). For topical cosmetic use systemic exposure is low but measurable; regulatory actions in the EU are moving to limit vitamin A equivalents in cosmetics and require labelling, reflecting concern over systemic exposure. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8884871/))

Безопасен ли retinyl palmitate при грудном вскармливании?

Mechanism and animal developmental data apply equally to lactation concerns because retinoids can be systemically available and transfer to offspring via milk when internal dose is sufficient; topical use gives low but measurable absorption so breastfeeding exposure is possible though expected to be low for normal cosmetic use. Regulatory guidance and safety reviews therefore treat vitamin A derivatives cautiously in pregnancy/lactation. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8884871/))

Безопасен ли retinyl palmitate для кожи малыша?

Do not change hazard or mechanism absent infant‑specific hazard data, but exposure is increased for infants (0–3 yr) because immature skin has higher permeability and greater surface‑area‑to‑weight; therefore exposure score is raised by +1 relative to adults. Animal developmental/teratogenic data indicate intrinsic hazard of the retinoid pathway; topical exposure to infants would warrant caution. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/8884871/))

Как VeriMom оценивает retinyl palmitate?

VeriMom оценивает retinyl palmitate в 13/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы retinyl palmitate при беременности?

См. наш список безопасных альтернатив retinyl palmitate с аналогичной функцией и классификацией без известных рисков.