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HIGH RISK

Стоит ли избегать retinoyl tetrapeptide-43 amide при беременности? | VeriMom

No harmonised CLP reproductive classification (no entry in ECHA Annex VI) and no CIR or SCCS safety assessment found for this specific ingredient (sources searched: ECHA Annex VI, CIR, SCCS, PubMed, CosIng, PubChem). However, the molecule contains a retinoyl (retinoid) moiety, which is a structural/class-based theoretical concern for developmental toxicity; there are no animal or human reproductive data for this specific peptide to elevate the hazard score. Topical peptide with large molecular weight and amide linkage suggests negligible systemic absorption under typical cosmetic use (hence exposure scored 0).

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли retinoyl tetrapeptide-43 amide при беременности?
No harmonised CLP reproductive classification (no entry in ECHA Annex VI) and no CIR or SCCS safety assessment found for this specific ingredient (sources searched: ECHA Annex VI, CIR, SCCS, PubMed, CosIng, PubChem). However, the molecule contains a retinoyl (retinoid) moiety, which is a structural/class-based theoretical concern for developmental toxicity; there are no animal or human reproductive data for this specific peptide to elevate the hazard score. Topical peptide with large molecular weight and amide linkage suggests negligible systemic absorption under typical cosmetic use (hence exposure scored 0).
Безопасен ли retinoyl tetrapeptide-43 amide при грудном вскармливании?
Same rationale as pregnancy: theoretical class-based concern due to retinoyl group but no specific reproductive or lactation transfer data. No regulatory harmonised flags or CIR/SCCS opinion for this ingredient. Expected topical absorption negligible, so low likelihood of significant transfer into breastmilk absent data.
Безопасен ли retinoyl tetrapeptide-43 amide для кожи малыша?
Hazard and mechanism remain theoretical (retinoid moiety) with no infant-specific data. Exposure increased by +1 relative to adult because infant skin has higher permeability and surface-area-to-weight, and although adult topical absorption is expected negligible, infant exposure is considered low but measurable in absence of definitive absorption data.
Как VeriMom оценивает retinoyl tetrapeptide-43 amide?
VeriMom оценивает retinoyl tetrapeptide-43 amide в 13/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы retinoyl tetrapeptide-43 amide при беременности?
См. наш список безопасных альтернатив retinoyl tetrapeptide-43 amide с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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