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Стоит ли избегать pueraria mirifica root powder/propylene glycol ferment filtrate при беременности? | VeriMom

Pueraria mirifica contains phytoestrogens (miroestrol/deoxymiroestrol/puerarin) with demonstrated estrogenic and antifertility effects in animal studies, supporting a suspected reproductive hazard for pregnant persons (animal reproductive/developmental signals). Mechanistically these act via estrogenic activity in vitro and in vivo. Topical cosmetic exposure is likely low-to-moderate systemic absorption (thus e=1), but systemic endocrine-active constituents raise concern for pregnancy. Sources: animal reproductive/estrogenic studies (PubMed) and CosIng/ingredient listings showing phytoestrogen content.

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли pueraria mirifica root powder/propylene glycol ferment filtrate при беременности?
Pueraria mirifica contains phytoestrogens (miroestrol/deoxymiroestrol/puerarin) with demonstrated estrogenic and antifertility effects in animal studies, supporting a suspected reproductive hazard for pregnant persons (animal reproductive/developmental signals). Mechanistically these act via estrogenic activity in vitro and in vivo. Topical cosmetic exposure is likely low-to-moderate systemic absorption (thus e=1), but systemic endocrine-active constituents raise concern for pregnancy. Sources: animal reproductive/estrogenic studies (PubMed) and CosIng/ingredient listings showing phytoestrogen content.
Безопасен ли pueraria mirifica root powder/propylene glycol ferment filtrate при грудном вскармливании?
Same basis as pregnancy: demonstrated estrogenic activity in animal studies suggests potential to affect hormonal milieu during lactation and possible transfer in breastmilk cannot be excluded. Topical use gives low but measurable systemic exposure in adults (e=1).
Безопасен ли pueraria mirifica root powder/propylene glycol ferment filtrate для кожи малыша?
Infants (0–3 yr) have higher skin permeability and surface-area-to-body-weight ratio; per scoring rules exposure is increased by +1 (adult e=1 → infant e=2). The hazard and mechanism are driven by the parent plant phytoestrogens with demonstrated estrogenic/antifertility effects in animals; therefore use on infant skin raises concern until ingredient-specific safety data for the ferment filtrate are available.
Как VeriMom оценивает pueraria mirifica root powder/propylene glycol ferment filtrate?
VeriMom оценивает pueraria mirifica root powder/propylene glycol ferment filtrate в 20/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы pueraria mirifica root powder/propylene glycol ferment filtrate при беременности?
См. наш список безопасных альтернатив pueraria mirifica root powder/propylene glycol ferment filtrate с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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