Стоит ли избегать psoralea corylifolia fruit extract при беременности? | VeriMom

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FAQ

Безопасен ли psoralea corylifolia fruit extract при беременности?

Animal and in vitro studies report embryotoxicity and reproductive/developmental effects for Psoralea corylifolia extracts and its constituents (psoralens, bakuchiol), supporting a suspected reproductive hazard (h=2). Reviews and primary studies describe embryotoxicity and developmental toxicity in animal models and identify estrogenic activity for bakuchiol (mechanism demonstrated → m=2). Topical exposure is plausibly systemically available for psoralens and other small lipophilic constituents (percutaneous absorption and phototoxicity documented) so exposure from cosmetics is moderate (e=2). Sources: PMC review (systematic toxicology summary) and primary embryotoxicity/reproductive studies. (See sources list.)

Безопасен ли psoralea corylifolia fruit extract при грудном вскармливании?

Because systemic maternal exposure is plausible and animal data indicate reproductive/developmental toxicity, the ingredient is rated as suspected (h=2) for breastfeeding. Mechanistic data (psoralens, bakuchiol with demonstrated bioactivity including estrogenic effects) support m=2. Dermal/topical use can result in systemic absorption of psoralens/bakuchiol (documented in percutaneous studies), so exposure to nursing parent is moderate (e=2); no reliable data on milk transfer were identified.

Безопасен ли psoralea corylifolia fruit extract для кожи малыша?

Infant-specific evidence was not found, so hazard and mechanism scores match adult (h=2, m=2). Exposure score increased by +1 for baby skin (immature barrier and higher surface-area-to-weight) from adult e=2 to e=3; psoralens and other small constituents in extracts have measurable dermal absorption/phototoxicity, raising exposure concern for 0–3 yr skin.

Как VeriMom оценивает psoralea corylifolia fruit extract?

VeriMom оценивает psoralea corylifolia fruit extract в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы psoralea corylifolia fruit extract при беременности?

См. наш список безопасных альтернатив psoralea corylifolia fruit extract с аналогичной функцией и классификацией без известных рисков.