Стоит ли избегать propylene glycol/sebacic acid/trimellitic anhydride copolymer при беременности? | VeriMom
No harmonised CMR classification or EU restriction was identified for this INCI; the CIR safety review of “trimellitic anhydride copolymers” (which includes Propylene Glycol/Sebacic Acid/Trimellitic Anhydride Copolymer) found very limited toxicology data, reported these ingredients as polymeric film‑formers used mainly in nail products, and concluded they would be expected to be safe for use in nail products at comparable concentrations. The polymer is high‑molecular‑weight and expected to sit on the surface (low dermal absorption). (CIR safety assessment).
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли propylene glycol/sebacic acid/trimellitic anhydride copolymer при беременности?
- No harmonised CMR classification or EU restriction was identified for this INCI; the CIR safety review of “trimellitic anhydride copolymers” (which includes Propylene Glycol/Sebacic Acid/Trimellitic Anhydride Copolymer) found very limited toxicology data, reported these ingredients as polymeric film‑formers used mainly in nail products, and concluded they would be expected to be safe for use in nail products at comparable concentrations. The polymer is high‑molecular‑weight and expected to sit on the surface (low dermal absorption). (CIR safety assessment).
- Безопасен ли propylene glycol/sebacic acid/trimellitic anhydride copolymer при грудном вскармливании?
- Same rationale as pregnancy: no harmonised H‑codes, no EU Annex II/III listing, and the CIR review found no reproductive/developmental data indicating risk from the polymeric ingredient itself. Expected low dermal absorption for the polymer means negligible exposure via topical cosmetic use during lactation; residual monomer levels were noted as possible but typically low. (CIR safety assessment).
- Безопасен ли propylene glycol/sebacic acid/trimellitic anhydride copolymer для кожи малыша?
- Hazard remains low because there is no harmonised CMR classification or EU restriction for the polymer itself, but the polymer can contain trace residual monomers (the CIR review states residual monomers may be present at low levels) and infant skin has higher permeability. Per your scoring rules, where adult exposure is essentially negligible but not proven completely non‑absorbable, infant exposure is increased by one. Thus a conservative exposure score of 1 for 0–3 yr skin is applied; hazard is scored 1 only as a cautious/class‑based flag (polymeric ingredient with potential residual monomer). (CIR safety assessment).
- Как VeriMom оценивает propylene glycol/sebacic acid/trimellitic anhydride copolymer?
- VeriMom оценивает propylene glycol/sebacic acid/trimellitic anhydride copolymer в 39/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы propylene glycol/sebacic acid/trimellitic anhydride copolymer при беременности?
- См. наш список безопасных альтернатив propylene glycol/sebacic acid/trimellitic anhydride copolymer с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.