VeriMomСтоит ли избегать propylene glycol isostearate при беременности? | VeriMom
No harmonised CLP reproductive classification (no reliable ECHA Annex VI entry found for CAS 68171-38-0), no EU Annex II/III listing, and the Cosmetic Ingredient Review (CIR) assessment of propylene glycol esters (covers propylene glycol mono‑/di/tri esters) reports safety under typical cosmetic uses; therefore no direct evidence of reproductive hazard. Databases (CosIng/SpecialChem, PubChem/ChemSpider) list physicochemical properties (very lipophilic, water solubility ~0.007 mg/L) suggesting low systemic dermal absorption but measurable exposure from leave‑on products, so exposure (e) scored 1 (low but measurable). Sources: CIR safety assessment, CosIng/SpecialChem, PubChem/ChemSpider.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли propylene glycol isostearate при беременности?
- No harmonised CLP reproductive classification (no reliable ECHA Annex VI entry found for CAS 68171-38-0), no EU Annex II/III listing, and the Cosmetic Ingredient Review (CIR) assessment of propylene glycol esters (covers propylene glycol mono‑/di/tri esters) reports safety under typical cosmetic uses; therefore no direct evidence of reproductive hazard. Databases (CosIng/SpecialChem, PubChem/ChemSpider) list physicochemical properties (very lipophilic, water solubility ~0.007 mg/L) suggesting low systemic dermal absorption but measurable exposure from leave‑on products, so exposure (e) scored 1 (low but measurable). Sources: CIR safety assessment, CosIng/SpecialChem, PubChem/ChemSpider.
- Безопасен ли propylene glycol isostearate при грудном вскармливании?
- Same rationale as pregnancy: no harmonised classification or regulatory ban, no convincing animal or human reproductive/developmental data found. Dermal exposure from cosmetics could give low but measurable systemic availability in some formulations, so e=1. No mechanism indicating transfer into breastmilk was identified in available sources.
- Безопасен ли propylene glycol isostearate для кожи малыша?
- No infant‑specific reproductive/toxicology data found; ingredient is a long‑chain, highly lipophilic monoester (logP estimated ~7–8) with low water solubility and no identified reproductive mechanism. Because infant skin (0–3 yr) has higher permeability and surface‑area:weight, increase exposure score by +1 (adult e=1 → baby e=2). No infant dermal toxicity studies located; CIR and cosmetic databases do not flag infant bans or restrictions.
- Как VeriMom оценивает propylene glycol isostearate?
- VeriMom оценивает propylene glycol isostearate в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы propylene glycol isostearate при беременности?
- См. наш список безопасных альтернатив propylene glycol isostearate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.