VeriMomСтоит ли избегать propylene glycol dioleate при беременности? | VeriMom
No harmonised ECHA reproductive classification (no CLH/H360) or SCCS/CIR safety assessment for propylene glycol dioleate was identified. No peer‑reviewed animal or human reproductive/developmental toxicity data for this specific ester were located. The compound is a large, lipophilic diester so a low but measurable dermal absorption is more plausible than extensive systemic uptake. Sources: ECHA substance information (no harmonised CLH listed), PubChem entry, and general toxicology reviews of propylene glycols which show no reproductive signal for the glycol family.
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли propylene glycol dioleate при беременности?
- No harmonised ECHA reproductive classification (no CLH/H360) or SCCS/CIR safety assessment for propylene glycol dioleate was identified. No peer‑reviewed animal or human reproductive/developmental toxicity data for this specific ester were located. The compound is a large, lipophilic diester so a low but measurable dermal absorption is more plausible than extensive systemic uptake. Sources: ECHA substance information (no harmonised CLH listed), PubChem entry, and general toxicology reviews of propylene glycols which show no reproductive signal for the glycol family.
- Безопасен ли propylene glycol dioleate при грудном вскармливании?
- No data found on lactational transfer or breastfeeding‑specific studies for propylene glycol dioleate. Given the low expected dermal absorption of a bulky diester, systemic exposure from normal cosmetic topical use is likely low; however hydrolysis to propylene glycol (which has known PK data) could theoretically increase systemic availability. No evidence of reproductive/developmental hazard for the dioleate itself was found.
- Безопасен ли propylene glycol dioleate для кожи малыша?
- There are no infant‑specific toxicity or safety studies for propylene glycol dioleate. Because infant skin (0–3 yr) has higher surface‑area‑to‑body‑weight and an immature barrier, I increased exposure scoring by +1 relative to adults (adult e=1 → baby e=2). No infant reproductive or mechanistic hazards were identified for the substance itself.
- Как VeriMom оценивает propylene glycol dioleate?
- VeriMom оценивает propylene glycol dioleate в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы propylene glycol dioleate при беременности?
- См. наш список безопасных альтернатив propylene glycol dioleate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.