Стоит ли избегать propylene glycol diisononanoate при беременности? | VeriMom
The Cosmetic Ingredient Review (CIR) Expert Panel lists propylene glycol diisononanoate (CAS 125804-17-3) among isononanoate/glycol esters concluded to be safe for cosmetic use in the uses/concentrations assessed; I found no harmonised ECHA CLP reproductive classification (H360/H361) nor peer‑reviewed reproductive toxicity studies indicating teratogenicity. Therefore there is no credible evidence of a pregnancy reproductive hazard for typical topical cosmetic use. ([cir-safety.org](https://cir-safety.org/sites/default/files/115_final_pelarg_rev2.pdf))
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли propylene glycol diisononanoate при беременности?
- The Cosmetic Ingredient Review (CIR) Expert Panel lists propylene glycol diisononanoate (CAS 125804-17-3) among isononanoate/glycol esters concluded to be safe for cosmetic use in the uses/concentrations assessed; I found no harmonised ECHA CLP reproductive classification (H360/H361) nor peer‑reviewed reproductive toxicity studies indicating teratogenicity. Therefore there is no credible evidence of a pregnancy reproductive hazard for typical topical cosmetic use. ([cir-safety.org](https://cir-safety.org/sites/default/files/115_final_pelarg_rev2.pdf))
- Безопасен ли propylene glycol diisononanoate при грудном вскармливании?
- No data were found showing mammary transfer, systemic reproductive toxicity, or harmonised lactation hazard; CIR concluded the ingredient safe as used in cosmetics and I found no peer‑reviewed evidence of effects on lactation or breastfed infants. Typical topical cosmetic use would therefore be expected to present negligible breastfeeding risk. ([cir-safety.org](https://cir-safety.org/sites/default/files/115_final_pelarg_rev2.pdf))
- Безопасен ли propylene glycol diisononanoate для кожи малыша?
- CIR concluded this ester is safe as used in cosmetics; I found no infant‑specific toxicology showing developmental or reproductive hazard. Dermal absorption data specific to infants were not located; given the chemical is a relatively large lipophilic glycol‑ester (low expected systemic absorption), adult exposure score is taken as negligible, but per instructions a modest increase for infant/0–3 yr skin is applied (e=+1) because immature barrier and higher surface‑area‑to‑weight can increase exposure if any absorption occurs. No evidence was found to raise hazard or mechanism scores. ([cir-safety.org](https://cir-safety.org/sites/default/files/115_final_pelarg_rev2.pdf))
- Как VeriMom оценивает propylene glycol diisononanoate?
- VeriMom оценивает propylene glycol diisononanoate в 39/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы propylene glycol diisononanoate при беременности?
- См. наш список безопасных альтернатив propylene glycol diisononanoate с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.