Стоит ли избегать podophyllum peltatum rhizome/root extract при беременности? | VeriMom

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Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли podophyllum peltatum rhizome/root extract при беременности?

Animal reproductive/embryotoxicity and human case reports with topical podophyllum/podophyllotoxin have led to clinical contraindication in pregnancy; regulatory listings (ECHA substance records list podophyllum resin under reproductive concern) and product monographs contraindicate use in pregnancy. Sources: epidemiologic/clinical review (PubMed/PMC), product monograph, ECHA substance info.

Безопасен ли podophyllum peltatum rhizome/root extract при грудном вскармливании?

Podophyllotoxin/podophyllin are not recommended during lactation; product monographs note excretion in human milk or lack of data and advise against breastfeeding during treatment. Mechanism is antimitotic (demonstrated), and systemic absorption from topical application can occur. See product monograph and clinical guidance.

Безопасен ли podophyllum peltatum rhizome/root extract для кожи малыша?

Hazard is driven by the parent antimitotic compound (podophyllotoxin) so h/m same as adults; dermal absorption is documented for topical podophyllotoxin/podophyllin formulations so infant exposure from topical cosmetic use on baby skin is higher (immature barrier and SA:BW) — exposure score increased by +1 for 0–3 yr.

Как VeriMom оценивает podophyllum peltatum rhizome/root extract?

VeriMom оценивает podophyllum peltatum rhizome/root extract в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.

Какие безопасные альтернативы podophyllum peltatum rhizome/root extract при беременности?

См. наш список безопасных альтернатив podophyllum peltatum rhizome/root extract с аналогичной функцией и классификацией без известных рисков.