Стоит ли избегать peg-25 oleamine при беременности? | VeriMom
No EU harmonised CLH (H360/H361) for PEG‑25 oleamine was identified; CIR (Cosmetic Ingredient Review) assessed the PEG‑cocamine/oleamine family and concluded the group (including PEG‑25 oleamine) is ‘‘safe in cosmetics in the present practices of use and concentration when formulated to be non‑irritating’’ while noting reproductive/developmental effects for some analogs at high oral doses in animals. Given the class/structural relationship to alkyl ethoxylated amines and the analog oral DART findings, a structural/class‑based caution is appropriate (h=1, m=1). Topical cosmetic exposure is expected to be low but measurable (e=1). Sources: CIR review, PubChem/ECHA product listings, EWG summary. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/pgcoca072015_FAR.pdf))
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли peg-25 oleamine при беременности?
- No EU harmonised CLH (H360/H361) for PEG‑25 oleamine was identified; CIR (Cosmetic Ingredient Review) assessed the PEG‑cocamine/oleamine family and concluded the group (including PEG‑25 oleamine) is ‘‘safe in cosmetics in the present practices of use and concentration when formulated to be non‑irritating’’ while noting reproductive/developmental effects for some analogs at high oral doses in animals. Given the class/structural relationship to alkyl ethoxylated amines and the analog oral DART findings, a structural/class‑based caution is appropriate (h=1, m=1). Topical cosmetic exposure is expected to be low but measurable (e=1). Sources: CIR review, PubChem/ECHA product listings, EWG summary. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/pgcoca072015_FAR.pdf))
- Безопасен ли peg-25 oleamine при грудном вскармливании?
- No specific lactation or milk‑transfer studies for PEG‑25 oleamine were found. By analogy to PEG‑amine class members (no specific DART via dermal exposure) and low expected systemic absorption from cosmetic topical use, hazard remains class/structure‑based (h=1) with theoretical mechanism only (m=1). Breastmilk exposure from topical use is likely low but measurable (e=1). ([cir-safety.org](https://www.cir-safety.org/sites/default/files/pgcoca072015_FAR.pdf))
- Безопасен ли peg-25 oleamine для кожи малыша?
- CIR reviewed PEG‑oleamine series and found the class acceptable ‘‘as used’’ when non‑irritating; no infant‑specific studies for 0–3‑year skin were located. Following your scoring rules, because dermal absorption is plausible (measurable) for PEG‑type ethoxylates, exposure for baby skin is increased by +1 (adult e=1 → baby e=2). Hazard and mechanism remain class/structural (h=1, m=1) absent direct infant data. Formulations causing irritation should be avoided for infant skin. ([cir-safety.org](https://www.cir-safety.org/sites/default/files/pgcoca072015_FAR.pdf))
- Как VeriMom оценивает peg-25 oleamine?
- VeriMom оценивает peg-25 oleamine в 27/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы peg-25 oleamine при беременности?
- См. наш список безопасных альтернатив peg-25 oleamine с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.