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Стоит ли избегать peg-10 propylene glycol при беременности? | VeriMom

No harmonised CLP reproductive (H360/H361 harmonised) classification for PEG‑10 propylene glycol was found; the Cosmetic Ingredient Review (CIR) re‑review (2016) found no developmental or reproductive (DART) studies and concluded the PEG‑propylene glycol esters (including PEG‑10 propylene glycol) are 'safe as used' in cosmetics. Registrations/notifications in ECHA dossiers sometimes show H361 as a self‑classification entry in registration dossiers or SDSs, but these are not harmonised classifications and do not override authoritative cosmetic safety assessments. Given the lack of DART data and CIR conclusion, hazard (h) is scored 0. Exposure (e) is low but measurable for topical cosmetic application in adults. Sources: CIR safety assessment; ECHA brief/profile noting non‑harmonised registration classifications; peer review on PEGs in dermatology.

ECHA regulatory hazard statements

  • H361

What to use instead

Pregnancy-safe ingredients that serve a similar function:

FAQ

Безопасен ли peg-10 propylene glycol при беременности?
No harmonised CLP reproductive (H360/H361 harmonised) classification for PEG‑10 propylene glycol was found; the Cosmetic Ingredient Review (CIR) re‑review (2016) found no developmental or reproductive (DART) studies and concluded the PEG‑propylene glycol esters (including PEG‑10 propylene glycol) are 'safe as used' in cosmetics. Registrations/notifications in ECHA dossiers sometimes show H361 as a self‑classification entry in registration dossiers or SDSs, but these are not harmonised classifications and do not override authoritative cosmetic safety assessments. Given the lack of DART data and CIR conclusion, hazard (h) is scored 0. Exposure (e) is low but measurable for topical cosmetic application in adults. Sources: CIR safety assessment; ECHA brief/profile noting non‑harmonised registration classifications; peer review on PEGs in dermatology.
Безопасен ли peg-10 propylene glycol при грудном вскармливании?
There are no animal or human reproductive/developmental data implicating PEG‑10 propylene glycol in lactation or pup effects, and CIR concluded safety 'as used'. Topical use leads to low but measurable exposure in adults; systemic availability from typical cosmetic use is expected to be low, so breastfeeding hazard/mechanism scores remain 0 and exposure 1. As with pregnancy, watch for potential low‑level impurities from ethoxylation processes (industry concern), but no specific evidence for transfer into breastmilk was identified.
Безопасен ли peg-10 propylene glycol для кожи малыша?
No infant‑specific reproductive or developmental adverse data were located for PEG‑10 propylene glycol. Because infant skin (0–3 yr) has a higher surface‑area‑to‑weight ratio and an immature barrier, the exposure score is increased by +1 compared with adults (adult e=1 → infant e=2). Hazard and mechanism remain 0 in the absence of DART or endocrine activity data; CIR found no genotoxicity/DART/carcinogenicity data for these PEG‑propylene glycol esters and concluded they are safe as used in cosmetics.
Как VeriMom оценивает peg-10 propylene glycol?
VeriMom оценивает peg-10 propylene glycol в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
Какие безопасные альтернативы peg-10 propylene glycol при беременности?
См. наш список безопасных альтернатив peg-10 propylene glycol с аналогичной функцией и классификацией без известных рисков.

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Медицинская оговорка

Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.

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