Стоит ли избегать p-vinylphenol при беременности? | VeriMom
No authoritative harmonised reproductive classification (ECHA Annex VI / Annex VI harmonised CLP H360/H361) or SCCS/CIR safety assessment for p‑vinylphenol was found. Registration and substance pages list the chemical (CAS 2628‑17‑3) but do not show a harmonised H360/H361 entry; supplier Safety Data Sheets list standard industrial GHS hazard statements but these appear to be self‑classifications rather than a harmonised Annex VI classification. No pregnancy‑specific reproductive toxicology studies on p‑vinylphenol were found in PubMed. Given the chemical is a small phenolic monomer (PubChem) with logP ≈2, dermal absorption from typical topical cosmetic use is likely low but measurable, so I scored exposure as 1 (low but measurable). Sources: ECHA substance/registration pages, PubChem/SDS; lack of SCCS/CIR/harmonised CLP documentation supports h=0 and m=0. ([echa.europa.eu](https://echa.europa.eu/registration-dossier/-/registered-dossier/26687/11?utm_source=openai))
ECHA regulatory hazard statements
- •H361
What to use instead
Pregnancy-safe ingredients that serve a similar function:
FAQ
- Безопасен ли p-vinylphenol при беременности?
- No authoritative harmonised reproductive classification (ECHA Annex VI / Annex VI harmonised CLP H360/H361) or SCCS/CIR safety assessment for p‑vinylphenol was found. Registration and substance pages list the chemical (CAS 2628‑17‑3) but do not show a harmonised H360/H361 entry; supplier Safety Data Sheets list standard industrial GHS hazard statements but these appear to be self‑classifications rather than a harmonised Annex VI classification. No pregnancy‑specific reproductive toxicology studies on p‑vinylphenol were found in PubMed. Given the chemical is a small phenolic monomer (PubChem) with logP ≈2, dermal absorption from typical topical cosmetic use is likely low but measurable, so I scored exposure as 1 (low but measurable). Sources: ECHA substance/registration pages, PubChem/SDS; lack of SCCS/CIR/harmonised CLP documentation supports h=0 and m=0. ([echa.europa.eu](https://echa.europa.eu/registration-dossier/-/registered-dossier/26687/11?utm_source=openai))
- Безопасен ли p-vinylphenol при грудном вскармливании?
- No evidence was found that p‑vinylphenol causes lactation/transfer‑to‑milk reproductive effects, and no authoritative food/cosmetic safety body (CIR/SCCS/harmonised CLP) has issued a specific reproductive/lactation warning for this chemical. Mechanistic data for placental or milk transfer are absent in the literature searched. Dermal exposure is low but measurable for adults, so exposure scored 1. ([echa.europa.eu](https://echa.europa.eu/registration-dossier/-/registered-dossier/26687/11?utm_source=openai))
- Безопасен ли p-vinylphenol для кожи малыша?
- There are no infant‑specific toxicology studies for topical p‑vinylphenol. Per the scoring rules, baby exposure is increased by +1 above adult exposure when measurable dermal absorption exists. Adult exposure was scored 1 (low but measurable), so infant exposure is 2 (moderate). No evidence was found that baby‑specific hazard or mechanism (higher h or m) applies. ([echa.europa.eu](https://echa.europa.eu/registration-dossier/-/registered-dossier/26687/11?utm_source=openai))
- Как VeriMom оценивает p-vinylphenol?
- VeriMom оценивает p-vinylphenol в 33/100 (высокий риск) на основе EU CosIng, классификаций ECHA и исследований PubMed.
- Какие безопасные альтернативы p-vinylphenol при беременности?
- См. наш список безопасных альтернатив p-vinylphenol с аналогичной функцией и классификацией без известных рисков.
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Медицинская оговорка
Данная информация предоставлена исключительно в образовательных целях и не является медицинской рекомендацией. Оценки безопасности основаны на общедоступных данных и могут не отражать все риски. Всегда консультируйтесь с вашим врачом перед использованием любых средств во время беременности или грудного вскармливания.